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GPR4 gene

Known as: G PROTEIN-COUPLED RECEPTOR 4, GPR4 
 
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
Acidic tissue microenvironment commonly exists in inflammatory diseases, tumors, ischemic organs, sickle cell disease, and many… Expand
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Highly Cited
2011
Highly Cited
2011
Endothelium-leukocyte interaction is critical for inflammatory responses. Whereas the tissue microenvironments are often acidic… Expand
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Highly Cited
2010
Highly Cited
2010
Proton receptors are G protein-coupled receptors that accept protons as ligands and function as pH sensors. One of the proton… Expand
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Highly Cited
2010
Highly Cited
2010
GPR4, previously proposed as the receptor for sphingosylphosphorylcholine, has recently been identified as the proton-sensing G… Expand
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Highly Cited
2006
Highly Cited
2006
The Galpha protein Gpa1 governs the cAMP-PKA signaling pathway and plays a central role in virulence and differentiation in the… Expand
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Highly Cited
2006
Highly Cited
2006
ABSTRACT GPR4 is a G protein-coupled receptor expressed in the vasculature, lung, kidney, and other tissues. In vitro ectopic… Expand
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Highly Cited
2006
Highly Cited
2006
Abundant evidence indicates that lysophosphatidylcholine (LPC) is proinflammatory and atherogenic. In the vascular endothelium… Expand
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2006
2006
G protein coupled receptors (GPCRs) form homo- and hetero-dimers or -oligomers, which are functionally important… Expand
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Highly Cited
2004
Highly Cited
2004
G2A (from G2 accumulation) is a G-protein-coupled receptor (GPCR) that regulates the cell cycle, proliferation, oncogenesis, and… Expand
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Highly Cited
2001
Highly Cited
2001
Sphingosylphosphorylcholine (SPC) and lysophosphatidylcholine (LPC) are bioactive lipid molecules involved in numerous biological… Expand
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