GNLY gene

Known as: T-LYMPHOCYTE ACTIVATION GENE 519, Granulysin Gene, LAG-2 
This gene is involved in the antimicrobial activity of cytotoxic T-lymphocytes and natural killer cells.
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
Recent data suggest that CD8+ T-cell effector activity is an important component in the control of HIV replication in elite… (More)
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Highly Cited
2011
Highly Cited
2011
The tumor microenvironment includes a complex network of immune T-cell subpopulations. In this study, we systematically analyzed… (More)
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Highly Cited
2009
Highly Cited
2009
The role of CD8 T cells in anti-tuberculosis immunity in humans remains unknown, and studies of CD8 T cell-mediated protection… (More)
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Review
2003
Review
2003
The human endometrium is an important site of innate immune defence, giving protection against uterine infection. Such protection… (More)
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Review
2001
Review
2001
The production of reactive oxygen intermediates and reactive nitrogen intermediates by innate immune cells is considered to be an… (More)
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Highly Cited
2001
Highly Cited
2001
Cytotoxic effector phenotype and function of MHC-restricted Mycobacterium tuberculosis (MTB)-reactive CD4(+) and CD8(+) T… (More)
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Highly Cited
1999
Highly Cited
1999
Cellular immunity against Mycobacterium tuberculosis controls infection in the majority of infected humans. Studies in mice have… (More)
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Highly Cited
1998
Highly Cited
1998
Cytolytic T lymphocytes (CTLs) kill intracellular pathogens by a granule-dependent mechanism. Granulysin, a protein found in… (More)
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Highly Cited
1998
Highly Cited
1998
A cDNA clone encoding the human homolog of rat Jagged1 was isolated from normal human marrow. Analyses of human stromal cell… (More)
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Highly Cited
1995
Highly Cited
1995
Ligands of the Delta/Serrate/lag-2 (DSL) family and their receptors, members of the lin-12/Notch family, mediate cell-cell… (More)
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