GNAO1 gene

Known as: GUANINE NUCLEOTIDE-BINDING PROTEIN, ALPHA-ACTIVATING ACTIVITY POLYPEPTIDE O, GNAO, G-ALPHA-o 
This gene is involved in the modulation of G protein signaling.
National Institutes of Health

Topic mentions per year

Topic mentions per year

2008-2017
051020082017

Papers overview

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2016
2016
OBJECTIVES Mutations in GNAO1 have been described in 11 patients to date. Although most of these individuals had epileptic… (More)
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2016
2016
De novo GNAO1 variants have been found in four patients including three patients with Ohtahara syndrome and one patient with… (More)
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2016
2016
GNAO1, located on chromosome 16q12.2, encodes for 1 of the heterotrimeric guanine binding proteins subunits (G proteins… (More)
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2016
2016
In 2 unrelated patients with axial hypotonia, developmental delay and a hyperkinetic movement disorder, a missense mutation was… (More)
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2015
2015
BACKGROUND The cause of infantile-onset epilepsy is complex and is not easily recognized clinically, particularly in paediatric… (More)
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2014
2014
Guanine nucleotide-binding protein (G protein), alpha activating activity polypeptide O (GNAO1) encodes an alpha subunit of the… (More)
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2013
2013
Heterotrimeric G proteins, composed of α, β, and γ subunits, can transduce a variety of signals from seven-transmembrane-type… (More)
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2013
2013
ETHNOPHARMACOLOGICAL RELEVANCE Chinese herbal medicines (HMs) is one of the great herbal systems of the world, which play an… (More)
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2013
2013
GNAO1 (guanine nucleotide-binding protein, α-activating activity polypeptide O) is a member of the subunit family of Gα proteins… (More)
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2011
2011
Heterotrimeric G proteins are molecular switches that control signal transduction, and their dysregulation can promote… (More)
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