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GM.CD40L cell vaccine
Known as:
GM.CD40L
A cell-based vaccine composed of irradiated tumor cells transduced with granulocyte-macrophage colony-stimulating factor (GM-CSF) and CD40-ligand…
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National Institutes of Health
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Papers overview
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2018
2018
A phase I/randomized phase II study of GM.CD40L vaccine in combination with CCL21 in patients with advanced lung adenocarcinoma
J. Gray
,
A. Chiappori
,
+15 authors
S. Antonia
Cancer Immunology and Immunotherapy
2018
Corpus ID: 52197888
The GM.CD40L vaccine, which recruits and activates dendritic cells, migrates to lymph nodes, activating T cells and leading to…
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2016
2016
Phase I/II randomized trial of GM.CD40L vaccine plus/minus CCL21 in advanced lung adenocarcinoma: Final results.
J. Gray
,
A. Chiappori
,
+8 authors
S. Antonia
2016
Corpus ID: 81523429
9037Background: Our GM.CD40L vaccine (an allogeneic tumor cell-based vaccine generated from human bystander cell line) recruits…
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2013
2013
A phase I/II randomized trial using GM-CSF-producing and CD40L-expressing bystander cell line (GM.CD40L) vaccine in combination with CCL21 in stage IV lung adenocarcinoma: Preliminary results.
J. Gray
,
A. Chiappori
,
+6 authors
S. Antonia
2013
Corpus ID: 79086934
3091 Background: Our GM.CD40L vaccine (an allogeneic tumor cell-based vaccine generated from human bystander cell line) recruits…
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2010
2010
Bystander vaccine therapy in mantle cell lymphoma (MCL): Phase II clinical results.
B. Shah
,
J. Tao
,
+7 authors
S. Dessureault
2010
Corpus ID: 74168067
2608 Background: A phase I study showed that vaccination of cancer patients with irradiated autologous tumor cells and GM.CD40L…
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2008
2008
Ongoing Studies with GM.CD40L Bystander-Based Vaccines
S. Dessureault
2008
Corpus ID: 195245687
2008
2008
Ongoing Studies with GM.CD40L Bystander-Based Vaccines
PhD Sophie Dessureault MD
Annals of Surgical Oncology
2008
Corpus ID: 21921425
Drs Kobayashi and colleagues are correct in pointing out that patient selection, sample size, heterogeneity of patient…
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2006
2006
A phase-I Trial Using a Universal GM-CSF-producing and CD40L-expressing Bystander Cell Line (GM.CD40L) in the Formulation of Autologous Tumor Cell-based Vaccines for Cancer Patients with Stage IV…
S. Dessureault
,
D. Noyes
,
+6 authors
S. Antonia
Annals of Surgical Oncology
2006
Corpus ID: 25591245
BackgroundSignificant antitumor T-cell responses are generated in vitro when human lymphocytes are stimulated with autologous…
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