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GM-CSF-encoding Oncolytic Adenovirus CGTG-102
Known as:
CGTG-102
A recombinant, oncolytic serotype 5/3 capsid-modified adenovirus encoding the immunostimulatory cytokine granulocyte-macrophage colony-stimulating…
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National Institutes of Health
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2015
2015
Oncolytic adenovirus and doxorubicin‐based chemotherapy results in synergistic antitumor activity against soft‐tissue sarcoma
M. Siurala
,
Simona Bramante
,
+9 authors
A. Hemminki
International Journal of Cancer
2015
Corpus ID: 27535394
Despite originating from several different tissues, soft‐tissue sarcomas (STS) are often grouped together as they share…
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2014
2014
Serotype chimeric oncolytic adenovirus coding for GM‐CSF for treatment of sarcoma in rodents and humans
Simona Bramante
,
A. Koski
,
+16 authors
A. Hemminki
International Journal of Cancer
2014
Corpus ID: 22657446
Sarcomas are a relatively rare cancer, but often incurable at the late metastatic stage. Oncolytic immunotherapy has gained…
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Highly Cited
2013
Highly Cited
2013
Antiviral and Antitumor T-cell Immunity in Patients Treated with GM-CSF–Coding Oncolytic Adenovirus
A. Kanerva
,
P. Nokisalmi
,
+15 authors
A. Hemminki
Clinical Cancer Research
2013
Corpus ID: 22630046
Purpose: Multiple injections of oncolytic adenovirus could enhance immunologic response. In the first part of this article, the…
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2012
2012
CGTG-102 (Ad5/3-D24-GMCSF), a novel oncolytic adenovirus, in patients with refractory solid tumors: Experience from an advanced therapy access program.
M. V. Euler
,
A. Kanerva
,
+10 authors
A. Hemminki
2012
Corpus ID: 78346817
e13035 Background: Following preclinical testing CGTG-102, a 5/3 chimeric oncolytic adenovirus armed with human GMCSF, has been…
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2010
2010
American Society of Gene & Cell Therapy--13th Annual Meeting.
G. Romano
IDrugs : the investigational drugs journal
2010
Corpus ID: 23535335
The American Society of Gene & Cell Therapy's 13th Annual Meeting, held in Washington, DC, included topics covering new…
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