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GM 6001

Known as: GM-6001, GM6001 
National Institutes of Health

Papers overview

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2012
2012
Increased expression of matrix metalloproteinases mediates thromboxane A2-induced invasion in lung cancer cells.
Thromboxane A(2) receptor (TP) has been shown to play an important role in multiple aspects of cancer development including… 
2009
2009
TGF-β1-Induced Expression of the Anti-Apoptotic PAI-1 Protein Requires EGFR Signaling.
TGF-β1 and its target gene encoding plasminogen activator inhibitor-1 (PAI-1) are major regulators of capillary outgrowth, vessel… 
2008
2008
Endothelial dependence of matrix metalloproteinase-mediated vascular hyporeactivity caused by lipopolysaccharide.
2006
2006
ADAM10-mediated Release of Complement Membrane Cofactor Protein during Apoptosis of Epithelial Cells*
Membrane cofactor protein CD46 controls complement activation on cells, is a receptor for several pathogens, and modulates immune… 
2005
2005
Reduction of myocardial infarct size by doxycycline: A role for plasmin inhibition
Myocardial ischemia-reperfusion (I/R) is associated with the activation of matrix metalloproteinases (MMPs) and serine proteases… 
2005
2005
Inhibition of collagenolytic activity relates to quantitative reduction of invasionin vitro in a c-Ha-ras transfected glial cell line
The function of proteases in brain tumor invasion is currently not well established. For tumors of epithelial and fibromatous… 
2004
2004
Co‐stimulation of human breast cancer cells with transforming growth factor‐β and tenascin‐C enhances matrix metalloproteinase‐9 expression and cancer cell invasion
Transforming growth factor‐β (TGF‐β), tenascin‐C (TN‐C) and matrix metalloproteinases (MMPs) have been demonstrated independently… 
2004
2004
Overexpression of Decorin by Rat Arterial Smooth Muscle Cells Enhances Contraction of Type I Collagen In Vitro
Objective—Overexpression of decorin reduces neointimal thickening in balloon-injured carotid arteries of rats by decreasing the… 
Highly Cited
2002
Highly Cited
2002
MT1‐MMP, but not secreted MMPs, influences the migration of human microvascular endothelial cells in 3‐dimensional collagen gels
Matrix metalloproteinases (MMPs) and their specific inhibitors the TIMPs play significant roles in angiogenesis. We investigated… 
1998
1998
Excessive synthesis of matrix metalloproteinases in exocrine tissues of NOD mouse models for Sjögren's syndrome.
OBJECTIVE Matrix metalloproteinases (MMP) and their substrates, components of the extracellular matrix, regulate environmental… 
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