GLI3 protein, human

Known as: GLI3, Glioma-Associated Oncogene Homolog 3 Protein, GLI-Kruppel Family Member 3 Protein 
Zinc finger protein GLI3 (1580 aa, ~170 kDa) is encoded by the human GLI3 gene. This protein is involved in transcriptional regulation, limb… (More)
National Institutes of Health

Papers overview

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2010
2010
Hedgehog (Hh) signaling in vertebrates depends on intraflagellar transport (IFT) within primary cilia. The Hh receptor Patched is… (More)
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2010
2010
Gli2 and Gli3 are primary transcriptional regulators that mediate hedgehog (Hh) signaling. Mechanisms that stabilize and… (More)
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Highly Cited
2007
Highly Cited
2007
Several studies have linked cilia and Hedgehog signaling, but the precise roles of ciliary proteins in signal transduction remain… (More)
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Highly Cited
2006
Highly Cited
2006
Gli3 is a zinc finger transcription factor proteolytically processed into a truncated repressor lacking C-terminal activation… (More)
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Highly Cited
2005
Highly Cited
2005
The intraflagellar transport (IFT) proteins Ift172/Wimple and Polaris/Ift88 and the anterograde IFT motor kinesin-II are required… (More)
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2005
2005
Hedgehog (Hh) signaling regulates cell differentiation and patterning in a wide variety of embryonic tissues. In vertebrates, at… (More)
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Highly Cited
2004
Highly Cited
2004
An important question is how the gradient of Hedgehog is interpreted by cells at the level of the Gli transcription factors. The… (More)
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Highly Cited
2000
Highly Cited
2000
Ci/Gli zinc finger proteins mediate the transcriptional effects of Hedgehog protein signals. In Drosophila, Ci action as… (More)
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Highly Cited
2000
Highly Cited
2000
Specification of distinct neuron types in the ventral spinal cord is thought to be mediated by a graded concentration of Sonic… (More)
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Highly Cited
2000
Highly Cited
2000
The secreted factor Sonic hedgehog (SHH) is both required for and sufficient to induce multiple developmental processes… (More)
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