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GLI2 gene

Known as: GLI kruppel family member 2 (GLI2) gene, GLI-Kruppel Family Member GLI2 Gene, ONCOGENE GLI2 
This gene is involved in transcriptional regulation and plays a role in sonic hedgehog signal transduction.
National Institutes of Health

Papers overview

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Highly Cited
2007
Highly Cited
2007
Hedgehog (Hh) and transforming growth factor-beta (TGF-beta) family members are involved in numerous overlapping processes during… Expand
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Highly Cited
2006
Highly Cited
2006
ABSTRACT Gli2 and Gli3 are the primary transcription factors that mediate Sonic hedgehog (Shh) signals in the mouse. Gli3 mainly… Expand
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Highly Cited
2006
Highly Cited
2006
The epithelial components of the mammary gland are thought to arise from stem cells with a capacity for self-renewal and… Expand
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Highly Cited
2002
Highly Cited
2002
The Shh signaling pathway is required in many mammalian tissues for embryonic patterning, cell proliferation and differentiation… Expand
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Highly Cited
2000
Highly Cited
2000
The secreted factor Sonic hedgehog (SHH) is both required for and sufficient to induce multiple developmental processes… Expand
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Highly Cited
1999
Highly Cited
1999
Gli family zinc finger proteins are mediators of Sonic hedgehog (Shh) signaling in vertebrates. The question remains unanswered… Expand
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Highly Cited
1998
Highly Cited
1998
Floor plate cells at the midline of the neural tube are specified by high-level activity of Sonic hedgehog (Shh) secreted by… Expand
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Highly Cited
1998
Highly Cited
1998
Induction of the floor plate at the ventral midline of the neural tube is one of the earliest events in the establishment of… Expand
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Highly Cited
1998
Highly Cited
1998
The expression of genes involved in the Sonic Hedgehog signalling pathway, including Shh, Ptc, Smo, Gli1, Gli2 and Gli3, were… Expand
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Highly Cited
1997
Highly Cited
1997
The correct patterning of vertebrate skeletal elements is controlled by inductive interactions. Two vertebrate hedgehog proteins… Expand
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