GJB2 protein, human

Known as: Connexin 26, Gap Junction Protein Beta 2, Connexin-26 
Gap junction beta-2 protein (226 aa, ~26 kDa) is encoded by the human GJB2 gene. This protein plays a role in gap junction-mediated facilitated… (More)
National Institutes of Health

Papers overview

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Highly Cited
2006
Highly Cited
2006
OBJECTIVES Mutations in connexin (Cx) 26 are the most common cause of nonsyndromic hereditary hearing impairments. Our goal is to… (More)
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Highly Cited
2005
Highly Cited
2005
H earing impairment is a common and highly heterogeneous sensory disorder. Genetic causes are thought to be responsible for more… (More)
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Highly Cited
2002
Highly Cited
2002
Keratitis-ichthyosis-deafness syndrome (KID) is a rare ectodermal dysplasia characterized by vascularizing keratitis, profound… (More)
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Highly Cited
2002
Highly Cited
2002
Lipid rafts are cholesterol-sphingolipid-rich microdomains that function as platforms for membrane trafficking and signal… (More)
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Highly Cited
1998
Highly Cited
1998
Intercellular connexin channels (gap junction channels) have long been thought to mediate molecular signaling between cells, but… (More)
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Highly Cited
1996
Highly Cited
1996
Normal human mammary epithelial cells express hcx43 and hCx26 proteins, which form functional gap junction channels. Both Cx… (More)
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Highly Cited
1995
Highly Cited
1995
DNAs coding for seven murine connexins (Cx) (Cx26, Cx31, Cx32, Cx37, Cx40, Cx43, and Cx45) are functionally expressed in human… (More)
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Highly Cited
1994
Highly Cited
1994
THE molecular mechanisms underlying the voltage dependence of intercellular channels formed by the family of vertebrate gap… (More)
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Highly Cited
1991
Highly Cited
1991
Gap junctions are formed by a family of homologous proteins termed connexins. Their channels are dodecamers, and homomeric forms… (More)
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Highly Cited
1989
Highly Cited
1989
While a number of different gap junction proteins have now been identified, hepatic gap junctions are unique in being the first… (More)
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