GIANT AXONAL NEUROPATHY 1

Known as: Neuropathy, Giant Axonal (GAN), Neuropathy, Giant Axonal, GIANT AXONAL NEUROPATHY 1, AUTOSOMAL RECESSIVE 
Rare autosomal recessive disorder of INTERMEDIATE FILAMENT PROTEINS. The disease is caused by mutations in the gene that codes gigaxonin protein. The… (More)

Topic mentions per year

Topic mentions per year

1968-2017
0204019682017

Papers overview

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2009
2009
Giant axonal neuropathy (GAN), a severe childhood disorder affecting both the peripheral nerves and the central nervous system… (More)
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2005
2005
BACKGROUND Giant axonal neuropathy (GAN) is a severe recessive disorder characterised by variable combination of progressive… (More)
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Highly Cited
2002
Highly Cited
2002
Axonal degeneration contributes to clinical disability in the acquired demyelinating disease multiple sclerosis. Axonal… (More)
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Highly Cited
2001
Highly Cited
2001
BACKGROUND Brain imaging studies detect abnormalities in normal-appearing white matter in patients with MS. OBJECTIVE To… (More)
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Highly Cited
2000
Highly Cited
2000
Disorganization of the neurofilament network is a prominent feature of several neurodegenerative disorders including amyotrophic… (More)
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Highly Cited
2000
Highly Cited
2000
Axonal injury occurs even in the earliest stages of multiple sclerosis. Magnetic resonance spectroscopic imaging (MRSI… (More)
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Highly Cited
1999
Highly Cited
1999
To characterize the distribution of apoptotic neurons and their relationships with the stage of disease, a history of HIV… (More)
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Highly Cited
1997
Highly Cited
1997
One of the histological hallmarks of early multiple sclerosis lesions is primary demyelination, with myelin destruction and… (More)
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1997
1997
Giant axonal neuropathy (GAN) is a rare autosomal recessive disorder described as a symmetrical distal neuropathy, with… (More)
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Highly Cited
1988
Highly Cited
1988
Based upon recent clinical findings, evidence exists that severe traumatic brain injury causes widespread axonal damage. In the… (More)
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