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GHRL gene
Known as:
ghrelin/obestatin prepropeptide
, MTLRP
, GROWTH HORMONE SECRETAGOGUE RECEPTOR LIGAND
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This gene is involved in regulating growth hormone release and satiety, thirst and anxiety.
National Institutes of Health
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Related topics
Related topics
5 relations
Appetite-Regulating Hormone
GHRL Protein
Intercellular Communication Process
ghrelin
Narrower (1)
GHRL wt Allele
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2009
2009
Obestatin stimulates Akt signalling in gastric cancer cells through beta-arrestin-mediated epidermal growth factor receptor transactivation.
C. J. Alvarez
,
Maria Lodeiro
,
M. Theodoropoulou
,
J. Camiña
,
F. Casanueva
,
Y. Pazos
Endocrine-Related Cancer
2009
Corpus ID: 207254446
Obestatin was identified as a gut peptide encoded by the ghrelin gene that interacts with the G protein-coupled receptor, GPR39…
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2009
2009
Identification and Genomic Sequence of a Ghrelin Receptor (GHS-R)-like Receptor in the Mozambique Tilapia, Oreochromis mossambicus
H. Kaiya
,
L. G. Riley
,
+4 authors
K. Kangawa
Zoological Science
2009
Corpus ID: 20916711
The growth hormone secretagogue-receptor (GHS-R) is an endogenous receptor for the gut hormone ghrelin (GRLN). Two isoforms of…
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Highly Cited
2008
Highly Cited
2008
Obestatin promotes survival of pancreatic beta-cells and human islets and induces expression of genes involved in the regulation of beta-cell mass and function.
R. Granata
,
F. Settanni
,
+12 authors
E. Ghigo
Diabetes
2008
Corpus ID: 30121703
OBJECTIVE Obestatin is a newly discovered peptide encoded by the ghrelin gene whose biological functions are poorly understood…
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Highly Cited
2008
Highly Cited
2008
Metabolic effects of chronic obestatin infusion in rats
S. Unniappan
,
M. Speck
,
T. Kieffer
Peptides
2008
Corpus ID: 30705970
2008
2008
Peripheral obestatin has no effect on feeding behavior and brain Fos expression in rodents
P. Kobelt
,
Anna-Sophia Wisser
,
+9 authors
H. Mönnikes
Peptides
2008
Corpus ID: 5405780
Highly Cited
2007
Highly Cited
2007
Circulating preprandial ghrelin to obestatin ratio is increased in human obesity.
Zhi-fu Guo
,
Xing Zheng
,
Yong-wen Qin
,
Jian-qiang Hu
,
Shao-ping Chen
,
Zeyu Zhang
Journal of Clinical Endocrinology and Metabolism
2007
Corpus ID: 32245100
CONTEXT Obestatin, a sibling of ghrelin derived from preproghrelin, opposes ghrelin's effects on food intake. Plasma obestatin…
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Highly Cited
2007
Highly Cited
2007
Effect of peripheral obestatin on gastric emptying and intestinal contractility in rodents
B. Smet
,
T. Thijs
,
Theo L. Peeters
,
I. Depoortere
Neurogastroenterology and Motility
2007
Corpus ID: 22811530
Abstract Obestatin has recently been discovered in the rat stomach. It is encoded by the ghrelin gene and has been claimed to be…
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2007
2007
Obestatin stimulates the secretion of pancreatic juice enzymes through a vagal pathway in anaesthetized rats - preliminary results.
M. Kapica
,
M. Zabielska
,
+4 authors
R. Zabielski
Journal of Physiology and Pharmacology
2007
Corpus ID: 21617222
Obestatin is a 23 amino acid peptide derived from the preproghrelin precursor, and originally purified from the rat stomach…
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Highly Cited
2006
Highly Cited
2006
Lack of interaction between peripheral injection of CCK and obestatin in the regulation of gastric satiety signaling in rodents
Guillaume Gourcerol
,
M. Million
,
+5 authors
Y. Taché
Peptides
2006
Corpus ID: 24764937
Highly Cited
2006
Highly Cited
2006
Seabream ghrelin: cDNA cloning, genomic organization and promoter studies.
C. Yeung
,
C. Chan
,
N. Woo
,
C. H. Cheng
Journal of Endocrinology
2006
Corpus ID: 15154165
Recent studies have indicated that ghrelin stimulates growth hormone release from the pituitary via the growth hormone…
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