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GHRL gene

Known as: ghrelin/obestatin prepropeptide, MTLRP, GROWTH HORMONE SECRETAGOGUE RECEPTOR LIGAND 
This gene is involved in regulating growth hormone release and satiety, thirst and anxiety.
National Institutes of Health

Related topics

Related topics

5 relations
Appetite-Regulating HormoneGHRL ProteinIntercellular Communication Processghrelin

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GHRL wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2013
Highly Cited
2013
Seven transmembrane G protein-coupled receptor repertoire of gastric ghrelin cells.
The molecular mechanisms regulating secretion of the orexigenic-glucoregulatory hormone ghrelin remain unclear. Based on qPCR… Expand
Highly Cited
2008
Highly Cited
2008
A single night of sleep deprivation increases ghrelin levels and feelings of hunger in normal‐weight healthy men
Sleep loss is currently proposed to disturb endocrine regulation of energy homeostasis leading to weight gain and obesity… Expand
Highly Cited
2007
Highly Cited
2007
Effects of obestatin on energy balance and growth hormone secretion in rodents.
Ghrelin stimulates food intake and adiposity and thereby increases body weight (BW) in rodents after central as well as… Expand
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Highly Cited
2007
Highly Cited
2007
Obestatin partially affects ghrelin stimulation of food intake and growth hormone secretion in rodents.
Administration of ghrelin, an endogenous ligand for the GH secretagogue receptor 1a (GHSR 1a), induces potent stimulating effects… Expand
Highly Cited
2006
Highly Cited
2006
Differential BBB interactions of three ingestive peptides: Obestatin, ghrelin, and adiponectin
Endogenous compounds, including ingestive peptides, can interact with the blood-brain barrier (BBB) in different ways. Here we… Expand
Highly Cited
2005
Highly Cited
2005
Obestatin, a Peptide Encoded by the Ghrelin Gene, Opposes Ghrelin's Effects on Food Intake
Ghrelin, a circulating appetite-inducing hormone, is derived from a prohormone by posttranslational processing. On the basis of… Expand
Highly Cited
2004
Highly Cited
2004
Common Structural Basis for Constitutive Activity of the Ghrelin Receptor Family*
Three members of the ghrelin receptor family were characterized in parallel: the ghrelin receptor, the neurotensin receptor 2 and… Expand
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Highly Cited
2002
Highly Cited
2002
Novel Expression and Functional Role of Ghrelin in Rat Testis.
Ghrelin, the endogenous ligand for the GH-secretagogue receptor (GHS-R), is a recently cloned peptide, primarily expressed in the… Expand
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Highly Cited
2001
Highly Cited
2001
Plasma ghrelin concentration and energy balance: overfeeding and negative energy balance studies in twins.
Central (intracerebral ventral) and peripheral (subcutaneous and intraperitoneal) administration of ghrelin causes obesity in… Expand
Highly Cited
2000
Highly Cited
2000
Purification and Characterization of Rat des-Gln14-Ghrelin, a Second Endogenous Ligand for the Growth Hormone Secretagogue Receptor*
Ghrelin, a peptide purified from the stomach, is an endogenous ligand for the growth hormone secretagogue receptor (GHS-R) and… Expand
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