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GHR, ASP152HIS

 
National Institutes of Health

Papers overview

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2018
2018
Significance In various animal species, including mammals, longevity can be extended by rapamycin, an inhibitor of mTOR… Expand
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2017
2017
Growth hormone receptor knockout (GHR-KO) mice are long lived with improved health span, making this an excellent model system… Expand
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2016
2016
GH receptor (GHR) and prolactin (PRL) receptor (PRLR) are homologous transmembrane cytokine receptors. Each prehomodimerizes and… Expand
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2016
2016
It has been reported that nuclear translocation of growth hormone receptor (GHR) may directly activate cell proliferation in… Expand
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2016
2016
INTRODUCTION Growth hormone deficiency is considered the most important factor determining skeletal fragility in hypopituitary… Expand
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2015
2015
BACKGROUND AND PURPOSE Brain cytochrome P450 2D (CYP2D) metabolises exogenous neurotoxins, endogenous substances and… Expand
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Highly Cited
2012
Highly Cited
2012
Genetic suppression of insulin/insulin-like growth factor signaling (IIS) can extend longevity in worms, insects, and mammals. In… Expand
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2007
2007
The GH receptor (GHR) mediates GH effects by activating the GHR-associated cytoplasmic tyrosine kinase, Janus kinase 2. Recent… Expand
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Highly Cited
2006
Highly Cited
2006
There is conflicting information on the physiological role of growth hormone (GH) in the control of aging. This study reports… Expand
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