Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

GHR, ASP152HIS

National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Significance In various animal species, including mammals, longevity can be extended by rapamycin, an inhibitor of mTOR… Expand
  • figure 1
  • table 1
  • table 2
  • figure 2
  • figure 3
2017
2017
Growth hormone receptor knockout (GHR-KO) mice are long lived with improved health span, making this an excellent model system… Expand
  • figure 2
  • figure 3
  • figure 4
  • figure 5
  • figure 6
2016
2016
GH receptor (GHR) and prolactin (PRL) receptor (PRLR) are homologous transmembrane cytokine receptors. Each prehomodimerizes and… Expand
2016
2016
Growth hormone deficiency is considered the most important factor determining skeletal fragility in hypopituitary patients… Expand
2016
2016
It has been reported that nuclear translocation of growth hormone receptor (GHR) may directly activate cell proliferation in… Expand
  • figure 1
  • table 1
  • figure 2
  • figure 3
  • figure 4
2015
2015
Brain cytochrome P450 2D (CYP2D) metabolises exogenous neurotoxins, endogenous substances and neurotransmitters. Brain CYP2D can… Expand
Highly Cited
2012
Highly Cited
2012
Genetic suppression of insulin/insulin-like growth factor signaling (IIS) can extend longevity in worms, insects, and mammals. In… Expand
  • figure 1
2007
2007
The GH receptor (GHR) mediates GH effects by activating the GHR-associated cytoplasmic tyrosine kinase, Janus kinase 2. Recent… Expand
Highly Cited
2006
Highly Cited
2006
There is conflicting information on the physiological role of growth hormone (GH) in the control of aging. This study reports… Expand
  • figure 1
  • figure 3
  • figure 2
  • figure 4