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GFI1B gene

Known as: GFI1B, growth factor independent 1B transcription repressor, Growth Factor Independent 1B (Potential Regulator of CDKN1A, Translocated in CML) Gene 
This gene plays a role in transcriptional regulation and erythroid cell growth. Translocations in the gene are associated with chronic myeloid… 
National Institutes of Health

Related topics

Related topics

8 relations
Blast Cell ProliferationErythropoiesisGFI1B protein, humanGFI1B wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Dominant negative Gfi1b mutations cause moderate thrombocytopenia and an impaired stress thrombopoiesis associated with mild erythropoietic abnormalities in mice.
GFI1B-related thrombocytopenia (GFI1B-RT) is a rare bleeding disorder mainly caused by the presence of truncated GFI1B proteins… 
2016
2016
An Autosomal-Recessive GFI1B Mutation Defines the Splice Isoform p37 As Essential for Biogenesis of Functional Human Platelets, but Dispensable for Erythropoiesis
Growth factor independent 1 (GFI1) and Growth Factor Independent 1B (GFI1B) are zinc finger transcriptional repressors that share… 
2016
2016
Reprogramming Mouse Embryonic Fibroblasts with Transcription Factors to Induce a Hemogenic Program.
This protocol details the induction of a hemogenic program in mouse embryonic fibroblasts (MEFs) via overexpression of… 
2014
2014
Zespół szarych płytek
Zespol szarych plytek (GPS) jest rzadko wystepującym, wrodzonym, dziedziczonym w sposob autosomalny recesywny lub dominujący… 
2013
2013
They're not your daddy's inherited platelet disorders anymore
Although individual inherited platelet disorders (IPDs) are rare, in aggregate – especially when including those IPDs resulting… 
2013
2013
“There will be blood” from fibroblasts
The blood system is continuously replenished from a rare population of hematopoietic stem cells (HSCs) that balance self-renewal… 
2013
2013
Growth Factor Independence 1b (Gfi1b) Regulates The Commitment, Differentiation and Expansion Of Hematopoietic Stem Cells
The efficacy of bone marrow stem cell transplantation is the therapy of choice for many hematopoietic diseases, in particular… 
2010
2010
Growth Factor Independence 1 b (Gfi1b) as a New Regulator of Hematopoietic Stem Cell Fate
Abstract 837 Donor matched transplantation of bone marrow or hematopoietic stem cells (HSCs) are widely used to treat… 
2004
2004
The Ubiquitin Ligase Triad1 Is Involved in Myelopoiesis and Interacts with the Transcriptional Repressors Gfi1 and Gfi1b.
We identified Triad1 as a gene that is upregulated by retinoic acid during the granulocytic differentiation of acute… 
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