FAQ

GDF5 wt Allele

Known as: LAP-4, SYNS2, BMP14 
Human GDF5 wild-type allele is located in the vicinity of 20q11.2 and is approximately 5 kb in length. This allele, which encodes growth… (More)

Topic mentions per year

Topic mentions per year

1996-2018
01219962018

Related topics

Related topics

10 relations
20q11.2Cell Differentiation processCell Proliferation Regulatory ProcessGDF5 protein, human
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Broader (1)

GDF5 gene

Related mentions per year

Related mentions per year

1937-2018
19401960198020002020
GDF5 wt Allele
Cell Differentiation process
Homo sapiens
Intercellular Communication Process
skeletal development
Cell Proliferation Regulatory Process

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Beta-arrestin1 and 2 differently modulate metabotropic glutamate receptor 7 signaling in rat developmental sevoflurane-induced neuronal apoptosis.
Beta-arrestins (β-arrs) are initially known as negative regulators of G protein-coupled receptors (GPCRs). Recently, there is… (More)
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2013
2013
A GDF5 Point Mutation Strikes Twice - Causing BDA1 and SYNS2
Growth and Differentiation Factor 5 (GDF5) is a secreted growth factor that belongs to the Bone Morphogenetic Protein (BMP… (More)
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2009
2009
In vitro engineering of fibrocartilage using CDMP1 induced dermal fibroblasts and polyglycolide.
This study was designed to explore the feasibility of using cartilage-derived morphogenetic protein-1 (CDMP1) induced dermal… (More)
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Highly Cited
2007
Highly Cited
2007
BMP-14 gene therapy increases tendon tensile strength in a rat model of achilles tendon injury.
  • Markus Rickert
  • The Journal of bone and joint surgery. American…
  • 2007
BACKGROUND Molecular and cellular-based enhancements of healing combined with conventional methods may yield better outcomes… (More)
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2005
2005
BMP-14 deficiency inhibits long bone fracture healing: a biochemical, histologic, and radiographic assessment.
OBJECTIVES Bone morphogenetic proteins (BMPs) represent a distinct subset of the transforming growth factor-beta family best… (More)
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2004
2004
Brachydactyly type C caused by a homozygous missense mutation in the prodomain of CDMP1.
Brachydactyly type C (BDC) is characterized by shortening of the middle phalanges of the index, middle, and little finger with… (More)
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2004
2004
Enhanced group II mGluR-mediated inhibition of pain-related synaptic plasticity in the amygdala
Pain has a strong emotional component. A key player in emotionality, the amygdala is also involved in pain processing. Our… (More)
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2001
2001
Facilitation and inhibition of retrieval in two aversive tasks in rats by intrahippocampal infusion of agonists of specific glutamate metabotropic receptor subtypes
Rationale: The generic antagonist of glutamate metabotropic receptors (mGlus), MCPG, blocks retrieval of inhibitory avoidance… (More)
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2000
2000
Cocaine and kindling alter the sensitivity of group II and III metabotropic glutamate receptors in the central amygdala.
G-protein-coupled metabotropic glutamate receptors (mGluRs) are being implicated in various forms of neuroplasticity and CNS… (More)
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2000
2000
Groups II and III metabotropic glutamate receptors differentially modulate brief and prolonged nociception in primate STT cells.
The heterogeneous family of G-protein-coupled metabotropic glutamate receptors (mGluRs) provides excitatory and inhibitory… (More)
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