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GDF5 wt Allele

Known as: LAP-4, SYNS2, BMP14 
Human GDF5 wild-type allele is located in the vicinity of 20q11.2 and is approximately 5 kb in length. This allele, which encodes growth… Expand
National Institutes of Health

Related topics

Related topics

10 relations
20q11.2Cell Differentiation processCell Proliferation Regulatory ProcessGDF5 protein, human
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Broader (1)

GDF5 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
A GDF5 Point Mutation Strikes Twice - Causing BDA1 and SYNS2
Growth and Differentiation Factor 5 (GDF5) is a secreted growth factor that belongs to the Bone Morphogenetic Protein (BMP… Expand
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2006
2006
Enhanced group II mGluR-mediated inhibition of pain-related synaptic plasticity in the amygdala
BackgroundThe latero-capsular part of the central nucleus of the amygdala (CeLC) is the target of the spino-parabrachio… Expand
Highly Cited
2004
Highly Cited
2004
Enhanced group III mGluR-mediated inhibition of pain-related synaptic plasticity in the amygdala
Pain has a strong emotional component. A key player in emotionality, the amygdala is also involved in pain processing. Our… Expand
2001
2001
Facilitation and inhibition of retrieval in two aversive tasks in rats by intrahippocampal infusion of agonists of specific glutamate metabotropic receptor subtypes
Abstract. Rationale: The generic antagonist of glutamate metabotropic receptors (mGlus), MCPG, blocks retrieval of inhibitory… Expand
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Highly Cited
2000
Highly Cited
2000
Platinum group elements in Kostomuksha komatiites and basalts: Implications for oceanic crust recycling and core-mantle interaction
We report precise PGE (Os, Ir, Ru, Pt, and Pd) concentrations for komatiite-basalt lava sequences of the Kostomuksha greenstone… Expand
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Highly Cited
2000
Highly Cited
2000
Groups II and III metabotropic glutamate receptors differentially modulate brief and prolonged nociception in primate STT cells.
The heterogeneous family of G-protein-coupled metabotropic glutamate receptors (mGluRs) provides excitatory and inhibitory… Expand
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Highly Cited
1997
Highly Cited
1997
Disruption of human limb morphogenesis by a dominant negative mutation in CDMP1
Chondrodysplasia Grebe type (CGT) is an autosomal recessive disorder characterized by severe limb shortening and dysmorphogenesis… Expand
Highly Cited
1996
Highly Cited
1996
Convulsant and anticonvulsant actions of agonists and antagonists of group III mGluRs.
Group III metabotropic glutamate receptors (mGluR4, 6, 7, 8) are negatively coupled to adenylate cyclase and, when activated… Expand
1995
1995
Production of hydroxy fatty acids from unsaturated fatty acids byFlavobacterium sp. DS5 hydratase, a C-10 positional- andcis unsaturation-specific enzyme
A new microbial isolate,Flavobacterium sp. DS5, converted oleic and linoleic acids to their corresponding 10-keto-and 10-hydroxy… Expand
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1986
1986
Expression of protooncogenes in murine osteosarcomas
The expression of 7 protooncogenes (c‐sis, c‐abl, c‐mos, c‐bas, c‐Ki‐ras, c‐fos, c‐myc) was examined in transplants and… Expand
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