GATA2 Transcription Factor

Known as: GATA Binding Protein 2, NFE1B Erythroid Transcription Factor, GATA2 
Endothelial transcription factor GATA-2 (480 aa, ~51 kDa) is encoded by the human GATA2 gene. This protein is involved in both sequence-specific DNA… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1995-2017
05019952017

Papers overview

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Review
2016
Review
2016
Myelodysplastic syndrome (MDS) is a clonal blood disorder characterized by ineffective hematopoiesis, cytopenias, dysplasia and… (More)
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Highly Cited
2014
Highly Cited
2014
Chromosomal rearrangements without gene fusions have been implicated in leukemogenesis by causing deregulation of proto-oncogenes… (More)
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Highly Cited
2012
Highly Cited
2012
Non-small cell lung cancer (NSCLC) is the most frequent cause of cancer deaths worldwide; nearly half contain mutations in the… (More)
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Highly Cited
2011
Highly Cited
2011
We report an allelic series of eight mutations in GATA2 underlying Emberger syndrome, an autosomal dominant primary lymphedema… (More)
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Highly Cited
2011
Highly Cited
2011
We report the discovery of GATA2 as a new myelodysplastic syndrome (MDS)-acute myeloid leukemia (AML) predisposition gene. We… (More)
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Highly Cited
2011
Highly Cited
2011
The syndrome of monocytopenia, B-cell and NK-cell lymphopenia, and mycobacterial, fungal, and viral infections is associated with… (More)
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Highly Cited
2010
Highly Cited
2010
Combinatorial transcription factor (TF) interactions control cellular phenotypes and, therefore, underpin stem cell formation… (More)
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Highly Cited
2009
Highly Cited
2009
Angiogenesis is controlled by physical interactions between cells and extracellular matrix as well as soluble angiogenic factors… (More)
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Highly Cited
2007
Highly Cited
2007
Androgen receptor (AR) is a ligand-dependent transcription factor that plays a key role in prostate cancer. Little is known about… (More)
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Highly Cited
1999
Highly Cited
1999
The mechanisms by which transient gradients of signaling molecules lead to emergence of specific cell types remain a central… (More)
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