GADD45A wt Allele

Known as: Growth Arrest- and DNA Damage-Inducible Gene GADD45, Alpha, Growth Arrest and DNA Damage-Inducible Gene 45, DNA Damage-Inducible Transcript-1 Gene 
Human GADD45A wild-type allele is located within 1p31.2-p31.1 and is approximately 3 kb in length. This allele, which encodes growth arrest and DNA… (More)
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
Humans differ from other animals in many aspects of anatomy, physiology, and behaviour; however, the genotypic basis of most… (More)
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Highly Cited
2005
Highly Cited
2005
Forkhead transcription factor, DAF-16, regulates genes that contribute both to longevity and resistance to various stresses in C… (More)
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Highly Cited
1999
Highly Cited
1999
The breast cancer susceptibility gene BRCA1 encodes a protein implicated in the cellular response to DNA damage, with postulated… (More)
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Highly Cited
1999
Highly Cited
1999
G1/S and G2/M cell cycle checkpoints maintain genomic stability in eukaryotes in response to genotoxic stress. We report here… (More)
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Highly Cited
1999
Highly Cited
1999
Recently Gadd45, a p53-regulated stress protein, has been implicated in the activation of a G2/M checkpoint after damage by UV… (More)
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Highly Cited
1998
Highly Cited
1998
The stress-responsive p38 and JNK MAPK pathways regulate cell cycle and apoptosis. A human MAPKKK, MTK1 (= MEKK4), mediates… (More)
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Highly Cited
1997
Highly Cited
1997
In the present study, we report the characterization of the p53 tumor suppressor pathway in the 60 cell lines of the National… (More)
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Highly Cited
1994
Highly Cited
1994
GADD45 is a ubiquitously expressed mammalian gene that is induced by DNA damage and certain other stresses. Like another p53… (More)
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Highly Cited
1994
Highly Cited
1994
A remarkable overlap was observed between the gadd genes, a group of often coordinately expressed genes that are induced by… (More)
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Highly Cited
1992
Highly Cited
1992
Cell cycle checkpoints can enhance cell survival and limit mutagenic events following DNA damage. Primary murine fibroblasts… (More)
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