GAC1 protein, human

Known as: leucine rich repeat neuronal 2, human, Glioma Amplified on Chromosome 1 Protein (Leucine-Rich), LRRN5 protein, human 
Glioma Amplified on Chromosome 1 Protein, encoded by the human GAC1 gene, belongs to the leucine-rich repeat superfamily. This gene was found to be… (More)
National Institutes of Health

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Broader (1)

Cell Adhesion Molecules, Neuronal
Homo sapiensIntegral Membrane ProteinsLRRN2 geneLRRN2 wt Allele
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Papers overview

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2012
2012
Glucose-induced posttranslational activation of protein phosphatases PP2A and PP1 in yeast
The protein phosphatases PP2A and PP1 are major regulators of a variety of cellular processes in yeast and other eukaryotes. Here… (More)
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2001
2001
Marked differences in unilateral isolated retinoblastomas from young and older children studied by comparative genomic hybridization
Although it is established that the loss of function of both alleles of the RB1 gene is a prerequisite for the development of… (More)
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2001
2001
Characterization of Gac1p, a regulatory subunit of protein phosphatase type I involved in glycogen accumulation in Saccharomyces cerevisiae
GAC1 and GLC7 encode regulatory and catalytic subunits, respectively, of a type 1 phosphatase (PP1) in Saccharomyces cerevisiae… (More)
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Highly Cited
1999
Highly Cited
1999
Amplification and overexpression of the MDM4 (MDMX) gene from 1q32 in a subset of malignant gliomas without TP53 mutation or MDM2 amplification.
We have previously reported on the amplification and overexpression of the MDM2 proto-oncogene in a subset of malignant gliomas… (More)
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1998
1998
Ssa1p chaperone interacts with the guanine nucleotide exchange factor of ras Cdc25p and controls the cAMP pathway in Saccharomyces cerevisiae.
We have found that the guanine nucleotide exchange factor for ras, Cdc25p, interacts with Ssa1p in Saccharomyces cerevisiae. This… (More)
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1998
1998
GAC1, a new member of the leucine-rich repeat superfamily on chromosome band 1q32.1, is amplified and overexpressed in malignant gliomas
We have used two-dimensional electrophoresis of enzyme-digested genomic DNA to identify a novel gene GAC1, which maps at 1q32.1… (More)
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1996
1996
Protein phosphatase type 1 interacts with proteins required for meiosis and other cellular processes in Saccharomyces cerevisiae.
Protein phosphatase type I (PP1) is involved in diverse cellular processes, and its activity toward specific substrates is… (More)
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Highly Cited
1995
Highly Cited
1995
Amino acid sequence and expression of the hepatic glycogen-binding (GL)-subunit of protein phosphatase-1.
A full-length cDNA encoding the putative hepatic glycogen-binding (GL) subunit of protein phosphatase-1 (PP1) was isolated from a… (More)
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1994
1994
The mutant type 1 protein phosphatase encoded by glc7-1 from Saccharomyces cerevisiae fails to interact productively with the GAC1-encoded regulatory subunit.
Loss-of-function gac1 mutants of Saccharomyces cerevisiae fail to accumulate normal levels of glycogen because of low glycogen… (More)
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1992
1992
GAC1 may encode a regulatory subunit for protein phosphatase type 1 in Saccharomyces cerevisiae.
Elevated dosage of the GAC1 gene from the yeast Saccharomyces cerevisiae causes hyperaccumulation of glycogen whereas a gene… (More)
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