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GAC1 protein, human
Known as:
leucine rich repeat neuronal 2, human
, Glioma Amplified on Chromosome 1 Protein (Leucine-Rich)
, LRRN5 protein, human
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Glioma Amplified on Chromosome 1 Protein, encoded by the human GAC1 gene, belongs to the leucine-rich repeat superfamily. This gene was found to be…
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National Institutes of Health
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Related topics
Related topics
10 relations
Broader (1)
Cell Adhesion Molecules, Neuronal
Homo sapiens
Integral Membrane Proteins
LRRN2 gene
LRRN2 wt Allele
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2012
Highly Cited
2012
Glucose-induced posttranslational activation of protein phosphatases PP2A and PP1 in yeast
D. Castermans
,
Ils Somers
,
+5 authors
J. Thevelein
Cell Research
2012
Corpus ID: 1872251
The protein phosphatases PP2A and PP1 are major regulators of a variety of cellular processes in yeast and other eukaryotes. Here…
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Review
2010
Review
2010
Bikaverin production and applications
M. Limón
,
Roberto Rodríguez-Ortiz
,
J. Avalos
Applied Microbiology and Biotechnology
2010
Corpus ID: 36303668
Bikaverin is a reddish pigment produced by different fungal species, most of them from the genus Fusarium, with antibiotic…
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Highly Cited
2003
Highly Cited
2003
Refined mapping of 1q32 amplicons in malignant gliomas confirms MDM4 as the main amplification target
M. Riemenschneider
,
C. Knobbe
,
G. Reifenberger
International Journal of Cancer
2003
Corpus ID: 38803139
We previously reported on the amplification and overexpression of the mouse double minute 4 homolog gene (MDM4) from 1q32 in a…
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Highly Cited
2001
Highly Cited
2001
Marked differences in unilateral isolated retinoblastomas from young and older children studied by comparative genomic hybridization
S. Herzog
,
D. Lohmann
,
+4 authors
H. Rieder
Human Genetics
2001
Corpus ID: 24106273
Abstract. Although it is established that the loss of function of both alleles of the RB1 gene is a prerequisite for the…
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Highly Cited
1999
Highly Cited
1999
Amplification and overexpression of the MDM4 (MDMX) gene from 1q32 in a subset of malignant gliomas without TP53 mutation or MDM2 amplification.
M. Riemenschneider
,
R. Büschges
,
+5 authors
G. Reifenberger
Cancer Research
1999
Corpus ID: 14403490
We have previously reported on the amplification and overexpression of the MDM2 proto-oncogene in a subset of malignant gliomas…
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Highly Cited
1998
Highly Cited
1998
GAC1, a new member of the leucine-rich repeat superfamily on chromosome band 1q32.1, is amplified and overexpressed in malignant gliomas
A. Almeida
,
Xiang Xiao Zhu
,
+7 authors
S. Hanash
Oncogene
1998
Corpus ID: 1623741
We have used two-dimensional electrophoresis of enzyme-digested genomic DNA to identify a novel gene GAC1, which maps at 1q32.1…
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Highly Cited
1996
Highly Cited
1996
Protein phosphatase type 1 interacts with proteins required for meiosis and other cellular processes in Saccharomyces cerevisiae
J. Tu
,
W. Song
,
M. Carlson
Molecular and Cellular Biology
1996
Corpus ID: 1425779
Protein phosphatase type I (PP1) is involved in diverse cellular processes, and its activity toward specific substrates is…
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Highly Cited
1995
Highly Cited
1995
Amino acid sequence and expression of the hepatic glycogen‐binding (GL‐subunit of protein phosphatase‐1
M. Doherty
,
G. Moorhead
,
N. Morrice
,
P. Cohen
,
P. Cohen
FEBS Letters
1995
Corpus ID: 7716602
Highly Cited
1994
Highly Cited
1994
The mutant type 1 protein phosphatase encoded by glc7-1 from Saccharomyces cerevisiae fails to interact productively with the GAC1-encoded regulatory subunit
J. Stuart
,
D. Frederick
,
C. M. Varner
,
K. Tatchell
Molecular and Cellular Biology
1994
Corpus ID: 33464869
Loss-of-function gac1 mutants of Saccharomyces cerevisiae fail to accumulate normal levels of glycogen because of low glycogen…
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Highly Cited
1992
Highly Cited
1992
GAC1 may encode a regulatory subunit for protein phosphatase type 1 in Saccharomyces cerevisiae.
J. Francois
,
S. Thompson-Jaeger
,
J. Skroch
,
U. Zellenka
,
W. Spevak
,
K. Tatchell
EMBO Journal
1992
Corpus ID: 24277042
Elevated dosage of the GAC1 gene from the yeast Saccharomyces cerevisiae causes hyperaccumulation of glycogen whereas a gene…
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