G-protein coupled adenosine receptor activity
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Level of adenosine, an endogenous astrocyte-based neuromodulator, is primarily regulated by adenosine P1 receptors. This study… Expand Ischemia is a multifactorial pathology characterized by different events evolving in the time. After ischemia a primary damage… Expand We previously demonstrated that uridine adenosine tetraphosphate (Up4A) exerts a potent vasodilator effect in the healthy porcine… Expand Under several adverse conditions, such as hypoxia or ischaemia, extracellular levels of adenosine are elevated because of… Expand P2 receptors that are activated by extracellular nucleotides (e.g., ATP, ADP, UTP, UDP, Ap(n)A) and P1 receptors activated by… Expand Effects of adenosine 5′-triphosphate (ATP) and adenosine on cardiac sinus pacemaker activity were examined in the rabbit heart… Expand The role of P1 receptors and P2Y1 receptors in coronary vasodilator responses to adenine nucleotides was examined in the isolated… Expand The present study examined the in vivo effects of ATP on the striatum of Sprague–Dawley rats. Intrastriatal administration of ATP… Expand OBJECTIVE
To assess the expression and function of purine receptors in articular chondrocytes.
Reverse transcriptase… Expand The selective GABA(C) receptor antagonist, (1,2,5,6-tetrahydropyridin-4-yl)methylphosphinic acid (TPMPA), is eight times more… Expand