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Furylfuramide

Known as: 2-Furanacetamide, alpha-((5-nitro-2-furanyl)methylene)-, Furylfuramide [Chemical/Ingredient] 
Used formerly as antimicrobial food additive. It causes mutations in many cell cultures and may be carcinogenic.
National Institutes of Health

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Related topics

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AF-2

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Mutagens
analogs & derivativesaspects of radiation effectschemical synthesisstandards characteristics

Papers overview

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2000
2000
Suppression of the furylfuramide-induced SOS response by monoterpenoids with a p-menthane skeleton using the Salmonella typhimurium TA1535/pSK1002 Umu test.
Suppression of the furylfuramide-induced SOS response by 25 kinds monoterpenoids (hydrocarbons, alcohols, ketones, and aldehydes… 
1994
1994
Effects of the umuDC, mucAB, and samAB operons on the mutational specificity of chemical mutagenesis in Escherichia coli: I. Frameshift mutagenesis.
Highly Cited
1993
Highly Cited
1993
Identification of heterogenous antimutagenic activities in the extract of edible brown seaweeds, Laminaria japonica (Makonbu) and Undaria pinnatifida (Wakame) by the umu gene expression system in…
Highly Cited
1988
Highly Cited
1988
X-ray- and chemically induced germ-line mutation causing phenotypical anomalies in mice.
1980
1980
Mutagenicity of nifurtimox in Escherichia coli.
Highly Cited
1979
Highly Cited
1979
Correlation between metabolic reduction rates and electron affinity of nitroheterocycles.
Nitroheterocyclic compounds can selectively sensitize hypoxic (tumor) cells to radiation damage in vitro. However, results in… 
1975
1975
Carcinogenicity of the food additive furylfuramide in foetal and young mice
FURYLFURAMIDE (so-called AF-2), 2-(2-furyl)-3-(5-nitro-2-furyl) acrylic acid amide, had been used widely (probably several tonnes… 
1975
1975
Mutagenic activity of furylfuramide on cultured mouse cells.
Effects of furylfuramide (FF) on cultured FM3A cells a C3H mouse mammary carcinoma cell line, were examined. FF inhibited the… 
1974
1974
Mutagenic and Recombinogenic Activities of the Food Additive Furylfuramide in Eukaryotes
The mutagenic and recombinogenic activities of furylfuramide, an antimicrobial food additive, were tested in a two-component… 
1971
1971
Effect of furylfuramide on reproduction and malformation.
As food additives are prone to be taken every day, it was considered important to test their effect on reproduction and their… 
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