Fumarylacetoacetase

Known as: fumarylacetoacetate fumarylhydrolase, fumarylacetoacetate hydrolase 
 
National Institutes of Health

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Highly Cited
2016
Highly Cited
2016
The combination of Cas9, guide RNA and repair template DNA can induce precise gene editing and the correction of genetic diseases… (More)
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2011
2011
UNLABELLED Hereditary tyrosinemia type I (HT1) results in hepatic failure, cirrhosis, and hepatocellular carcinoma (HCC) early in… (More)
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2010
2010
BACKGROUND & AIMS Hepatocyte-like cells can be derived from pluripotent stem cells such as embryonic stem (ES) cells, but ES cell… (More)
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2008
2008
BACKGROUND/AIMS The AKT survival pathway is involved in a wide variety of human cancers. We investigated the implication of this… (More)
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2006
2006
Tyrosine catabolism is an essential pathway in animals, but its role in plants is unclear. The first steps of tyrosine… (More)
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Review
2002
Review
2002
Hereditary tyrosinaemia type I (HT I) (McKusick 276700) is caused by a deficiency of fumarylacetoacetate hydrolase (FAH) activity… (More)
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2001
2001
Hereditary tyrosinemia type 1 (HT1) is a severe autosomal recessive metabolic disease associated with point mutations in the… (More)
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1999
1999
Hereditary tyrosinemia type I and alkaptonuria are disorders of tyrosine catabolism caused by deficiency of fumarylacetoacetate… (More)
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Highly Cited
1996
Highly Cited
1996
Current strategies for hepatic gene therapy are either quantitatively inefficient or suffer from lack of permanent gene… (More)
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1981
1981
A patient is described with type I tyrosinemia characterized by urinary excretion of succinylacetone together with increased… (More)
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