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Frontotemporal Lobar Degeneration

Known as: Degenerations, Frontotemporal Lobar, Lobar Degenerations, Frontotemporal, FTLD 
Heterogeneous group of neurodegenerative disorders characterized by frontal and temporal lobe atrophy associated with neuronal loss, gliosis, and… 
National Institutes of Health

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DementiaFrontotemporal dementiaIn BloodMicrobiological

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Highly Cited
2016
Highly Cited
2016
Prevalence, characteristics, and survival of frontotemporal lobar degeneration syndromes
Objectives: To estimate the lifetime risk, prevalence, incidence, and mortality of the principal clinical syndromes associated… 
Highly Cited
2010
Highly Cited
2010
TDP-43 transgenic mice develop spastic paralysis and neuronal inclusions characteristic of ALS and frontotemporal lobar degeneration
Neuronal cytoplasmic and intranuclear aggregates of RNA-binding protein TDP-43 are a hallmark feature of neurodegenerative… 
Review
2010
Review
2010
Clinical, genetic and pathological heterogeneity of frontotemporal dementia: a review
Frontotemporal dementia (FTD) is the second most common young-onset dementia and is clinically characterised by progressive… 
Highly Cited
2009
Highly Cited
2009
TDP-43 mutant transgenic mice develop features of ALS and frontotemporal lobar degeneration
Frontotemporal lobar degeneration (FTLD) and amyotrophic lateral sclerosis (ALS) are neurodegenerative diseases that show… 
Highly Cited
2009
Highly Cited
2009
TARDBP mutations in motoneuron disease with frontotemporal lobar degeneration
TDP‐43 (TAR‐DNA binding protein) aggregates in neuronal inclusions in motoneuron disease (MND), as well as in frontotemporal… 
Highly Cited
2009
Highly Cited
2009
Consensus criteria for the diagnosis of frontotemporal cognitive and behavioural syndromes in amyotrophic lateral sclerosis
Amyotrophic lateral sclerosis (ALS) is increasingly recognized to be a multisystem disorder which includes both clinical and… 
Highly Cited
2008
Highly Cited
2008
Phosphorylated TDP‐43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis
TAR DNA‐binding protein of 43kDa (TDP‐43) is deposited as cytoplasmic and intranuclear inclusions in brains of patients with… 
Highly Cited
2008
Highly Cited
2008
Nomenclature for neuropathologic subtypes of frontotemporal lobar degeneration: consensus recommendations
Nomenclature for neuropathologic subtypes of frontotemporal lobar degeneration : consensus recommendations 
Review
2007
Review
2007
Frontotemporal lobar degeneration: clinical and pathological relationships
Frontotemporal lobar degeneration (FTLD) encompasses a heterogeneous group of clinical syndromes that include frontotemporal… 
Highly Cited
2006
Highly Cited
2006
Pathological heterogeneity of frontotemporal lobar degeneration with ubiquitin-positive inclusions delineated by ubiquitin immunohistochemistry and novel monoclonal antibodies.
Frontotemporal lobar degeneration with ubiquitin-positive inclusions (FTLD-U) is a common neuropathological subtype of… 
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