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Fractalkine

Known as: Chemokine (C-X3-C Motif) Ligand 1, Chemokine CX3CL1 [Chemical/Ingredient], Neurotactin 
A CX3C chemokine that is a transmembrane protein found on the surface of cells. The soluble form of chemokine CX3CL1 can be released from cell… 
National Institutes of Health

Related topics

Related topics

13 relations
CX3CL1 geneIn BloodNrt protein, DrosophilaProcess of secretion

Narrower (1)

CX3CL1 protein, human

Broader (1)

chemokine

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
Chemokine Fractalkine Attenuates Overactivation and Apoptosis of BV-2 Microglial Cells Induced by Extracellular ATP
Microglia, the resident macrophages of the central nervous system (CNS), are activated by a myriad of signaling molecules… 
2011
2011
Chemokine (CCR) and fractalkine (CX3CR) receptors and end stage renal disease
Objective and designGenetic polymorphisms of chemokines and their receptors were reported to be independent risk factors for… 
2010
2010
Sec5, a member of the exocyst complex, mediates Drosophila embryo cellularization
Cellularization of the Drosophila embryo is the process by which a syncytium of ∼6000 nuclei is subdivided into discrete cells… 
2009
2009
Generating substrate bound functional chemokine gradients in vitro.
2007
2007
Activation of human natural killer cells by recombinant membrane-expressed fractalkine on the surface of tumor cells.
Chemokine receptors are typically expressed on natural killer cells, which can be activated by membrane ligands including the… 
2004
2004
Viral Macrophage Inflammatory Protein-II and Fractalkine (CX3CL1) Chimeras Identify Molecular Determinants of Affinity, Efficacy, and Selectivity at CX3CR1
Fractalkine (FKN/CX3CL1) is a cell surface-expressed chemokine involved in many aspects of leukocyte trafficking and activation… 
Highly Cited
2002
Highly Cited
2002
Cloning of a novel rainbow trout (Oncorhynchus mykiss) CC chemokine with a fractalkine-like stalk and a TNF decoy receptor using cDNA fragments containing AU-rich elements.
An activation-specific cDNA library was made from phytohaemagglutinin (PHA)-activated haematopoietic cells of the rainbow trout… 
Highly Cited
2001
Highly Cited
2001
Deregulation of the expression of the fractalkine/fractalkine receptor complex in HIV-1-infected patients.
Fractalkine is the only member of the CX3C chemokine family. Polymorphism of the fractalkine receptor gene may influence the… 
Highly Cited
2001
Highly Cited
2001
Soluble interleukin-6 receptor alpha inhibits the cytokine-Induced fractalkine/CX3CL1 expression in human vascular endothelial cells in culture.
Soluble form of IL-6 receptor alpha (sIL-6R) is known to serve as an agonist, without exogenous IL-6, on endothelial cells which… 
1999
1999
The role of chemokines in the pathogenesis of multiple sclerosis.
Chemokines are a rapidly expanding family of small, secreted, 8-12 kDa, heparin-binding chemotactic cytokines, which are… 
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