Fluorine F 18 SKI-249380

Known as: F-SKI249380, [18F] SKI-249380, [18F]-N-(2-chloro-6-methylphenyl)-2-(6-(4-(2-fluoroethyl)piperazin-1-yl)-2-methylpyrimidin-4-ylamino)thiazole-5-carboxamide 
A radioconjugate composed of a derivative of the multi-targeted kinase inhibitor dasatinib conjugated to the radioisotope fluorine F 18, with… (More)
National Institutes of Health

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1990-2016
01219902016

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2016
2016
Several antecedent studies had reported close relationship between low body weight and Parkinson's disease (PD). However, there… (More)
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2012
2012
Dasatinib, a new-generation Src and platelet-derived growth factor receptor (PDGFR) inhibitor, is currently under evaluation in… (More)
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2007
2007
Although [18F] fluoropropylcarbomethoxyiodophenylnortropane (FP-CIT) is a promising radiopharmaceutical for dopamine transporter… (More)
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2006
2006
UNLABELLED The cell adhesion molecule integrin alpha v beta 3 plays a key role in tumor angiogenesis and metastasis. A series of… (More)
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2005
2005
The brain serotonin-2A receptor (5-HT2AR) has been implicated in both the pathology of schizophrenia and the therapeutic action… (More)
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2004
2004
We report the results of a double-blind, randomized prospective trial on D2 and 5-HT2 receptor occupancy and the clinical effects… (More)
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2003
2003
Multiple sclerosis is an autoimmune disease, which characterized by CNS myelin lesion. The pathological changes include distinct… (More)
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1999
1999
A synthetic procedure for the routine preparation of [18F] N-3-fluoropropyl-2-beta-carbomethoxy-3-beta-(4' methylphenyl… (More)
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1996
1996
A procedure for the routine preparation of [18F]FP-CIT has been developed. Purification of the final product was achieved by… (More)
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1990
1990
The relation between white-matter lesions (WMLs), demonstrated with magnetic resonance imaging, and regional cerebral blood flow… (More)
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