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Fluorine F 18 Fluorthanatrace

Known as: [18F]FTT, [18F]FluorThanatrace 
A radiotracer consisting of an analogue of the poly(ADP-ribose) polymerase 1 (PARP1) inhibitor rucaparib radiolabeled with the positron emitting… Expand
National Institutes of Health

Papers overview

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2018
2018
Preliminary evaluation of a novel 18F-labeled PARP-1 ligand for PET imaging of PARP-1 expression in prostate cancer.
INTRODUCTION Poly (ADP-ribose) polymerase-1 (PARP-1) plays many roles in prostate cancer (PC), such as mediating DNA damage… Expand
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2018
2018
Abstract A054: Real-time imaging of PARP-1 in ovarian cancer
Introduction: Poly(ADP-ribose) polymerase inhibitors (PARPi) are emerging targeted therapeutics for the treatment of ovarian… Expand
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2017
2017
PARP-1 Expression Quantified by [18F]FluorThanatrace: A Biomarker of Response to PARP Inhibition Adjuvant to Radiation Therapy.
INTRODUCTION Poly (ADP-ribose) polymerase 1 (PARP-1) is the major target of clinical PARP inhibitors and is a potential… Expand
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2016
2016
Abstract A02: A novel orthotopic ovarian patient derived xenograft model platform to investigate novel therapies for BRCA deficient ovarian cancers
Introduction: To create a personalized, targeted approach to high grade serous ovarian cancers (HGSOC), reliable preclinical… Expand
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