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First in Human

Known as: firstInHuman 
The first time an active substance or agent is administered to a human during a study.
National Institutes of Health

Papers overview

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2018
2018
Introduction. VSV-IFNβ-NIS is an oncolytic vesicular stomatitis virus (VSV; Rhabdovirus family) with rapid replication kinetics… Expand
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2017
2017
This commentary reflects the collective view of pharmaceutical scientists from four different organizations with extensive… Expand
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2017
2017
Cell cloning and subsequent process development activities are on the critical path directly impacting the timeline for… Expand
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2017
2017
The long journey of developing a drug from initial discovery target identification to regulatory approval often leaves many… Expand
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2016
2016
3079Background: Stimulating effector T cells is an attractive anti-cancer therapeutic strategy. PF-8600 is a novel fully human… Expand
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2016
2016
Accelerator mass spectrometry (AMS) is an ultra-sensitive technique for the analysis of radiocarbon. It is applicable to… Expand
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2016
2016
On October 5, 1981, Fortune magazine published a cover article entitled the “Next Industrial Revolution: Designing Drugs by… Expand
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2015
2015
There are limited treatment options for patients with recurrent glioblastoma (GBM). The EnGeneIC delivery vehicle (EDV) is a… Expand
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2011
2011
This issue of the Journal of Pharmacological and Toxicological Methods (JPTM) is themed. It is the eighth in a series, arising… Expand
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2010
2010
PurposeConatumumab is a fully human monoclonal agonist antibody against human death receptor 5 (DR5). The primary objectives of… Expand
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