Skip to search form
Skip to main content
Skip to account menu
Semantic Scholar
Semantic Scholar's Logo
Search 210,023,882 papers from all fields of science
Search
Sign In
Create Free Account
Fexofenadine hydrochloride
Known as:
Benzeneacetic Acid, 4-(1-Hydroxy-4-(4-(hydroxydiphenylmethyl)-1-piperidinyl)butyl)-alpha,alpha-dimethyl-, Hydrochloride
, Fexofenadine HCl
The hydrochloride salt form of fexofenadine, a carboxylated metabolic derivative of terfenadine and second generation, long-lasting selective…
Expand
National Institutes of Health
Create Alert
Alert
Related topics
Related topics
13 relations
Narrower (1)
Allegra
Drug Allergy
Fexofenadine hydrochloride 180 MG Oral Tablet
Fexofenadine hydrochloride 180 MG Oral Tablet [Allegra]
Fexofenadine hydrochloride 180 MG Oral Tablet [Wal-Fex]
Expand
Broader (1)
Terfenadine
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2005
Highly Cited
2005
CONTRIBUTION OF OATP (ORGANIC ANION-TRANSPORTING POLYPEPTIDE) FAMILY TRANSPORTERS TO THE HEPATIC UPTAKE OF FEXOFENADINE IN HUMANS
Maki Shimizu
,
K. Fuse
,
+4 authors
Y. Sugiyama
Drug Metabolism And Disposition
2005
Corpus ID: 8867727
Fexofenadine hydrochloride (FEX), a second generation H1-receptor antagonist, is mainly eliminated from the liver into bile in…
Expand
Highly Cited
2005
Highly Cited
2005
Fexofenadine pharmacokinetics are associated with a polymorphism of the SLCO1B1 gene (encoding OATP1B1).
M. Niemi
,
K. Kivistö
,
U. Hofmann
,
M. Schwab
,
M. Eichelbaum
,
M. Fromm
British Journal of Clinical Pharmacology
2005
Corpus ID: 11846004
The H1-receptor antagonist fexofenadine is a P-glycoprotein substrate [1]. However, the effects of genetic polymorphisms of the…
Expand
Highly Cited
2004
Highly Cited
2004
Validation of the Dermatology Life Quality Index as an outcome measure for urticaria-related quality of life.
R. Lennox
,
M. Leahy
Annals of Allergy, Asthma & Immunology
2004
Corpus ID: 39484333
Highly Cited
2004
Highly Cited
2004
A variant 2677A allele of the MDR1 gene affects fexofenadine disposition
S. Yi
,
K. Hong
,
+8 authors
Sang‐Goo Shin
Clinical pharmacology and therapy
2004
Corpus ID: 6182470
Highly Cited
2003
Highly Cited
2003
Addition of fexofenadine to a topical corticosteroid reduces the pruritus associated with atopic dermatitis in a 1‐week randomized, multicentre, double‐blind, placebo‐controlled, parallel‐group study
M. Kawashima
,
T. Tango
,
T. Noguchi
,
M. Inagi
,
H. Nakagawa
,
S. Harada
British Journal of Dermatology
2003
Corpus ID: 25338555
Summary Background Fexofenadine, a nonsedating, H1‐receptor selective antihistamine, exhibits consistent efficacy and safety in…
Expand
Highly Cited
2002
Highly Cited
2002
MDR1 gene polymorphisms and disposition of the P-glycoprotein substrate fexofenadine.
S. Drescher
,
E. Schaeffeler
,
+5 authors
M. Fromm
British Journal of Clinical Pharmacology
2002
Corpus ID: 27000245
AIMS The C3435T polymorphism in the human MDR1 gene is associated with lower intestinal P-glycoprotein expression, reduced…
Expand
Highly Cited
2000
Highly Cited
2000
Comparison of the efficacy, safety and quality of life provided by fexofenadine hydrochloride 120 mg, loratadine 10 mg and placebo administered once daily for the treatment of seasonal allergic…
van CAUWENBERGE
,
Juniper
Clinical and Experimental Allergy
2000
Corpus ID: 42471985
As there have been no previously published studies, this multinational, double‐blind, randomized, placebo‐controlled, parallel…
Expand
Highly Cited
2000
Highly Cited
2000
Fexofenadine HCl is safe and effective for treatment of chronic idiopathic urticaria.
H. Nelson
,
R. Reynolds
,
J. Mason
Annals of Allergy, Asthma & Immunology
2000
Corpus ID: 46033416
Review
1999
Review
1999
Once-daily fexofenadine HCl improves quality of life and reduces work and activity impairment in patients with seasonal allergic rhinitis.
E. Meltzer
,
T. Casale
,
R. Nathan
,
A. Thompson
Annals of Allergy, Asthma & Immunology
1999
Corpus ID: 37771667
Highly Cited
1999
Highly Cited
1999
A double-blind, placebo-controlled trial of fexofenadine HCl in the treatment of chronic idiopathic urticaria.
A. Finn
,
A. Kaplan
,
R. Fretwell
,
R. Qu
,
J. Long
Journal of Allergy and Clinical Immunology
1999
Corpus ID: 44501886
By clicking accept or continuing to use the site, you agree to the terms outlined in our
Privacy Policy
(opens in a new tab)
,
Terms of Service
(opens in a new tab)
, and
Dataset License
(opens in a new tab)
ACCEPT & CONTINUE