Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

Fexofenadine hydrochloride

Known as: Benzeneacetic Acid, 4-(1-Hydroxy-4-(4-(hydroxydiphenylmethyl)-1-piperidinyl)butyl)-alpha,alpha-dimethyl-, Hydrochloride, Fexofenadine HCl 
The hydrochloride salt form of fexofenadine, a carboxylated metabolic derivative of terfenadine and second generation, long-lasting selective… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2005
Highly Cited
2005
Fexofenadine hydrochloride (FEX), a second generation H1-receptor antagonist, is mainly eliminated from the liver into bile in… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
2005
Highly Cited
2005
The H1-receptor antagonist fexofenadine is a P-glycoprotein substrate [1]. However, the effects of genetic polymorphisms of the… Expand
Is this relevant?
Highly Cited
2004
Highly Cited
2004
There have been considerable disagreements regarding the influence of MDR1 (ABCB1) polymorphisms on the disposition of P… Expand
Is this relevant?
Highly Cited
2003
Highly Cited
2003
Summary Background Fexofenadine, a nonsedating, H1‐receptor selective antihistamine, exhibits consistent efficacy and safety in… Expand
Is this relevant?
Highly Cited
2002
Highly Cited
2002
AIMS The C3435T polymorphism in the human MDR1 gene is associated with lower intestinal P-glycoprotein expression, reduced… Expand
Is this relevant?
Highly Cited
2000
Highly Cited
2000
As there have been no previously published studies, this multinational, double‐blind, randomized, placebo‐controlled, parallel… Expand
Is this relevant?
Highly Cited
2000
Highly Cited
2000
BACKGROUND Fexofenadine is a nonsedating antihistamine approved for treatment of seasonal allergic rhinitis. OBJECTIVE This… Expand
Is this relevant?
Highly Cited
1999
Highly Cited
1999
BACKGROUND Fexofenadine hydrochloride (HCl) is a new H(1) antihistamine used twice daily in some countries. OBJECTIVE A… Expand
Is this relevant?
Highly Cited
1999
Highly Cited
1999
BACKGROUND Symptoms of chronic idiopathic urticaria (CIU) include relentless itching and painful wheals, which can be physically… Expand
Is this relevant?
Highly Cited
1998
Highly Cited
1998
Fexofenadine is a selective, nonsedating H1‐receptor antagonist that relieves symptoms of allergic conditions. 
Is this relevant?