Fexofenadine hydrochloride

Known as: Benzeneacetic Acid, 4-(1-Hydroxy-4-(4-(hydroxydiphenylmethyl)-1-piperidinyl)butyl)-alpha,alpha-dimethyl-, Hydrochloride, Fexofenadine HCl 
The hydrochloride salt form of fexofenadine, a carboxylated metabolic derivative of terfenadine and second generation, long-lasting selective… (More)
National Institutes of Health

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Narrower (1)

Allegra
Drug AllergyFexofenadine hydrochloride 180 MG Oral TabletFexofenadine hydrochloride 180 MG Oral Tablet [Allegra]Fexofenadine hydrochloride 180 MG Oral Tablet [Wal-Fex]
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Broader (1)

Terfenadine

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2011
2011
Poloxamer/cyclodextrin/chitosan-based thermoreversible gel for intranasal delivery of fexofenadine hydrochloride.
To enhance permeation and solubility of an intranasal delivery system of fexofenadine hydrochloride (FXD HCl), a new formulation… (More)
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2010
2010
Preparation and evaluation of spray-dried hyaluronic acid microspheres for intranasal delivery of fexofenadine hydrochloride.
Hyaluronic acid (HA)-based microspheres containing PEG 6000 and/or sodium taurocholate (NaTC) were prepared by the spray-drying… (More)
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Highly Cited
2005
Highly Cited
2005
Contribution of OATP (organic anion-transporting polypeptide) family transporters to the hepatic uptake of fexofenadine in humans.
Fexofenadine hydrochloride (FEX), a second generation H(1)-receptor antagonist, is mainly eliminated from the liver into bile in… (More)
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2005
2005
Capillary electrophoresis method for fexofenadine hydrochloride in capsules.
A simple, accurate, and effective capillary electrophoresis method with ultraviolet absorbance detection was developed and… (More)
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2004
2004
A variant 2677A allele of the MDR1 gene affects fexofenadine disposition.
BACKGROUND AND OBJECTIVES There have been considerable disagreements regarding the influence of MDR1 (ABCB1) polymorphisms on the… (More)
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Highly Cited
2002
Highly Cited
2002
MDR1 gene polymorphisms and disposition of the P-glycoprotein substrate fexofenadine.
AIMS The C3435T polymorphism in the human MDR1 gene is associated with lower intestinal P-glycoprotein expression, reduced… (More)
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2000
2000
Fexofenadine HCl is safe and effective for treatment of chronic idiopathic urticaria.
BACKGROUND Fexofenadine is a nonsedating antihistamine approved for treatment of seasonal allergic rhinitis. OBJECTIVE This… (More)
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1999
1999
Double-blind, placebo-controlled study comparing the efficacy and safety of fexofenadine hydrochloride (120 and 180 mg once daily) and cetirizine in seasonal allergic rhinitis.
BACKGROUND Fexofenadine hydrochloride (HCl) is a new H(1) antihistamine used twice daily in some countries. OBJECTIVE A… (More)
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1998
1998
Pharmacokinetics, pharmacodynamics, and tolerance of single- and multiple-dose fexofenadine hydrochloride in healthy male volunteers.
BACKGROUND Fexofenadine is a selective, nonsedating H1-receptor antagonist that relieves symptoms of allergic conditions… (More)
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1997
1997
Efficacy and safety of fexofenadine hydrochloride for treatment of seasonal allergic rhinitis.
BACKGROUND H1-receptor antagonists are effective for the treatment of seasonal allergic rhinitis. In rare circumstances, some… (More)
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