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Fatty Acid Synthases

Known as: Acid Synthases, Fatty, Synthetases, Fatty Acid, Fatty Acid Synthetases 
Enzymes that catalyze the synthesis of FATTY ACIDS from acetyl-CoA and malonyl-CoA derivatives.
National Institutes of Health

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16 relations

Narrower (8)

FAS1 protein, S cerevisiaeFAS2 protein, S cerevisiaeFatty-acid synthasePks2 protein, Mycobacterium tuberculosis
FASN geneIn BloodProcess of secretionantagonists & inhibitors

Papers overview

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Highly Cited
1991
Highly Cited
1991
Isolation and sequencing of a genomic DNA clone containing the 3' terminus of the 6-methylsalicylic acid polyketide synthetase gene of Penicillium urticae.
A 7.7-kilobase (kb) Penicillium urticae genomic DNA fragment containing the 3' terminus of the 6-methylsalicylic acid polyketide… 
1979
1979
Synthesis of long chain acyl-enzyme thioesters by modified fatty acid synthetases and their hydrolysis by a mammary gland thioesterase.
Highly Cited
1979
Highly Cited
1979
Physicochemical studies of the rat liver and adipose fatty acid synthetases.
Highly Cited
1978
Highly Cited
1978
Properties of the thioesterase component obtained by limited trypsinization of the fatty acid synthetase multienzyme complex.
Highly Cited
1976
Highly Cited
1976
One-step purification and properties of a two-peptide fatty acid synthetase from the uropygial gland of the goose.
Cell-free extracts from the uropygial gland of goose catalyzed the incorporation of malonyl-CoA into normal fatty acids and… 
1976
1976
On the 4'-phosphopantetheine content of chicken and rat liver fatty acid synthetases.
Highly Cited
1975
Highly Cited
1975
Presence of two polypeptide chains comprising fatty acid synthetase.
Highly purified fatty acid synthetases of chicken and rat livers have molecular weights of 500,000 and dissociate in solutions of… 
1975
1975
Malonyl and palmityl transferase-less mutants of the yeast fatty-acid-synthetase complex.
146 independently isolated mutants of the fatty acid synthetase gene locus fas 1 were subdivided into six different… 
Highly Cited
1973
Highly Cited
1973
Pantetheine-free mutants of the yeast fatty-acid-synthetase complex.
Among 52 Saccharomyces cerevisiae fatty acid synthetase (fas)mutants screened for their ability to incorporate 14C-labeled… 
1971
1971
Fatty acid synthetase from lactating rat mammary gland. 3. Dissociation and reassociation.
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