Farnesylation Inhibition

Farnesylation Inhibition involves interference with, or restraint of, enzymatic activities involved in covalent addition of farnesyl group(s) (three… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

2004-2015
0120042015

Papers overview

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2015
2015
The number of laminopathies is large, and the variability is equally wide. OMIM mentions 10 different entities, but there are… (More)
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2010
2010
This phase I study was performed to determine the safety profile, maximum tolerated dose (MTD) and biological activity of… (More)
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2007
2007
In previous studies we found that the GTPase p21 Harvey-Ras (Ha-Ras) stimulates the production of reactive oxygen species and… (More)
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Highly Cited
2005
Highly Cited
2005
Hutchinson-Gilford progeria syndrome (HGPS) is typically caused by mutations in codon 608 (G608G) of the LMNA gene, which… (More)
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2004
2004
PURPOSE Tipifarnib, an orally bioavailable inhibitor of farnesyl transferase, has activity in hematologic malignancies, but the… (More)
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