Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

Farnesyl-diphosphate farnesyltransferase

Known as: FPP-FPP Farnesyl Transferase, Farnesyl Diphosphate Farnesyltransferase, Presqualene Diphosphate Synthase 
The first committed enzyme of the biosynthesis pathway that leads to the production of STEROLS. it catalyzes the synthesis of SQUALENE from farnesyl… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2009
2009
Farnesyl pyrophosphate (FPP), a key intermediate in the mevalonate pathway and protein farnesylation, can act as an agonist for… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 6
Is this relevant?
2008
2008
Nitrogenous bisphosphonate inhibitors of farnesyl disphosphate synthase have been used clinically for treatment of bone disease… Expand
Is this relevant?
Highly Cited
2007
Highly Cited
2007
Lewis-acid catalysts such as AlMe3, AlMe2Cl, and BPh3 significantly improve the efficiency of the nickel-catalyzed arylcyanation… Expand
Is this relevant?
2007
2007
Macrophage cyclooxygenase‐2 (COX‐2) plays an important role in prostaglandin E2 and throm‐boxane A2 production. Statins are… Expand
Is this relevant?
Highly Cited
2006
Highly Cited
2006
In order to investigate whether products derived from the oxidation of sebum can be responsible for the induction of inflammatory… Expand
Is this relevant?
Highly Cited
2005
Highly Cited
2005
Undecaprenyl pyrophosphate synthase (UPPs) catalyzes the consecutive condensation reactions of a farnesyl pyrophosphate (FPP… Expand
  • table I
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
2001
Highly Cited
2001
To evaluate the effects of sterol regulatory element-binding proteins (SREBPs) on the expression of the individual enzymes in the… Expand
Is this relevant?
2001
2001
Lithiation of the N-2,4,6-triisopropylbenzenesulfonyl-2-pyrroline (16) and treatment of the resulting cyclic vinyllithium reagent… Expand
Is this relevant?
Highly Cited
1998
Highly Cited
1998
Bisphosphonates are currently the most important class of antiresorptive drugs used for the treatment of metabolic bone diseases… Expand
Is this relevant?
Highly Cited
1988
Highly Cited
1988
Addition of elicitor, cell wall fragments of the fungus Phytophthora parasitica, to tobacco cell suspension cultures (Nicotiana… Expand
Is this relevant?