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FapyAde

Known as: FAPy 
National Institutes of Health

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1 relation

Broader (1)

4,6-diamino-5-N-formamidopyrimidine

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
Unexpected non-Hoogsteen-based mutagenicity mechanism of FaPy-DNA lesions.
8-Oxopurines (8-oxodG and 8-oxodA) and formamidopyrimidines (FaPydG and FaPydA) are major oxidative DNA lesions involved in… 
2011
2011
Bypass of Aflatoxin B1 Adducts by the Sulfolobus solfataricus DNA Polymerase IV
Aflatoxin B1 (AFB1) is oxidized to an epoxide in vivo, which forms an N7-dG DNA adduct (AFB1–N7-dG). The AFB1–N7-dG can rearrange… 
2008
2008
The Energetics of Rearrangement and Water Elimination Reactions in the Radiolysis of the DNA Bases in Aqueous Solution (eaq− and ·OH Attack): DFT Calculations
Abstract Naumov, S. and von Sonntag, C. The Energetics of Rearrangement and Water Elimination Reactions in the Radiolysis of the… 
2004
2004
Isolation of a formamidopyrimidine-DNA glycosylase (fpg) mutant of Escherichia coli K12
SummaryThe fpg+ gene of Escherichia coli coding for formamidopyrimidine-DNA glycosylase was previously cloned on a multicopy… 
2002
2002
Site-specific hydroxylation at polyguanosine in double-stranded DNA by nickel(II) in the presence of SH compounds: comparison with singlet oxygen-induced DNA damage.
We examined the mechanism of DNA damage induced by carcinogenic Ni(II) in the presence of SH compounds. In the presence of model… 
2000
2000
Fapyadenine is a moderately efficient chain terminator for prokaryotic DNA polymerases.
Highly Cited
1999
Highly Cited
1999
Synthesis and enzymatic processing of oligodeoxynucleotides containing tandem base damage.
Several studies have shown that ionizing radiation generates a wide spectrum of lesions to DNA including base modifications… 
1997
1997
Near Ultraviolet Radiation (UVA and UVB) Causes a Formamidopyrimidine Glycosylase‐Dependent Increase in G to T Transversions
In contrast to far-UV (< 290 nm) DNA damage, a large fraction of the DNA damage caused by near-UV is oxygen-dependent, suggesting… 
Highly Cited
1995
Highly Cited
1995
Oxidative modification of DNA bases in rat liver and lung during chemical carcinogenesis and aging.
1994
1994
Formamidopyrimidine DNA glycosylase in the yeast Saccharomyces cerevisiae.
A DNA glycosylase that excises, 2,6-diamino-4-hydroxy-5N-methylformamidopyrimidine (Fapy) from double stranded DNA has been… 
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