FAQ

Fanconi Anemia Group J Protein

Known as: BRCA1/BRCA2-Associated Helicase 1, BRCA1-Associated C-Terminal Helicase 1, BRCA1-Binding Helicase-Like Protein BACH1 
Fanconi anemia group J protein (1249 aa, ~141 kDa) is encoded by the human BRIP1 gene. This protein is involved in DNA-dependent ATPase activity, 5… (More)

Topic mentions per year

Topic mentions per year

1995-2016
02419952016

Related topics

Related topics

5 relations
BRIP1 geneDNA RepairDNA Repair GeneFanconi Anemia
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Related mentions per year

Related mentions per year

1940-2018
19401960198020002020
Fanconi Anemia Group J Protein
DNA Repair
Fanconi Anemia
DNA Repair Gene
BRIP1 gene
Fanconi Anemia Group M Protein

Papers overview

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2016
2016
Conflicting Interpretation of Genetic Variants and Cancer Risk by Commercial Laboratories as Assessed by the Prospective Registry of Multiplex Testing
Purpose Massively parallel sequencing allows simultaneous testing of multiple genes associated with cancer susceptibility… (More)
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2016
2016
BRIP1 inhibits the tumorigenic properties of cervical cancer by regulating RhoA GTPase activity
Breast cancer 1, early onset (BRCA1)-interacting protein 1 (BRIP1), a DNA-dependent adenosine triphosphatase and DNA helicase, is… (More)
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2016
2016
Overexpression of the BRIP1 ameliorates chemosensitivity to cisplatin by inhibiting Rac1 GTPase activity in cervical carcinoma HeLa cells.
BRCA1-interacting protein 1 (BRIP1), a DNA-dependent ATPase and a DNA helicase, is critical for BRCA-associated DNA damage repair… (More)
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2016
2016
Elementary: breast cancer culprits leave their signatures on the double helix
SherlockHolmeswas renowned for his ability to discern subtle clues imprinted on people’s history to solve a case. A study… (More)
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2013
2013
The Forkhead Box M1 protein regulates BRIP1 expression and DNA damage repair in epirubicin treatment
FOXM1 is implicated in genotoxic drug resistance but its role and mechanism of action remain unclear. Here, we establish that… (More)
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Review
2012
Review
2012
[Present status and tasks for genetic testing and risk-reducing surgery in patients with hereditary breast and ovarian cancer].
In Japan, awareness of hereditary breast and ovarian cancer (HBOC) has gradually increased among health care workers and the… (More)
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2010
2010
Thermodynamic study of the BRCT domain of BARD1 and its interaction with the -pSER-X-X-Phe- motif-containing BRIP1 peptide.
The BRCA1-associated RING domain protein 1 (BARD1) is the heterodimeric partner of BRCA1. The BRCA1/BARD1 complex demonstrates… (More)
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1998
1998
Purification and characterization of adenosine diphosphate ribose pyrophosphatase from human erythrocytes.
Free ADP-ribose is a turnover product of NAD+, protein-bound polymeric and monomeric ADP-ribose, and cyclic ADP-ribose. But… (More)
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1997
1997
Rat liver ADP-ribose pyrophosphatase-I as an in vitro target of the acetaminophen metabolite N-acetyl-p-benzoquinoneimine.
N-acetyl-p-benzoquinoneimine (NAPQI) is the metabolite responsible for acetaminophen hepatotoxicity. ADP-ribose pyrophosphatase-I… (More)
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1995
1995
Inhibition and ADP-ribose pyrophosphatase-I by nitric-oxide-generating systems: a mechanism linking nitric oxide to processes dependent on free ADP-ribose.
Rat liver ADP-ribose pyrophosphatase-I (ADPRibase-I; EC 3.6.1.13) hydrolyzes ADP-ribose with high specificity and a low Km. Thus… (More)
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