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Familial Hemiplegic Migraine

Known as: Familial Hemiplegic Migraines, Hemiplegic Migraine, Familial, Hemiplegic-Ophthalmoplegic Migraine 
A migraine disorder characterized by individual and family history of aura that includes motor weakness.
National Institutes of Health

Related topics

Related topics

4 relations

Broader (2)

Migraine DisordersMigraine with Aura
Migraine with Acute Onset AuraNervous system structure

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2011
Highly Cited
2011
Increased Susceptibility to Cortical Spreading Depression in the Mouse Model of Familial Hemiplegic Migraine Type 2
Familial hemiplegic migraine type 2 (FHM2) is an autosomal dominant form of migraine with aura that is caused by mutations of the… 
Highly Cited
2010
Highly Cited
2010
Calcitonin gene-related peptide triggers migraine-like attacks in patients with migraine with aura
Introduction: Calcitonin gene-related peptide (CGRP) is a key molecule in migraine pathogenesis. Intravenous CGRP infusion… 
Review
2009
Review
2009
Molecular genetics of migraine
Migraine is an episodic neurovascular disorder that is clinically divided into two main subtypes that are based on the absence or… 
Highly Cited
2004
Highly Cited
2004
Alternating hemiplegia of childhood or familial hemiplegic migraine?: A novel ATP1A2 mutation
Alternating hemiplegia of childhood (AHC) is typically distinguished from familial hemiplegic migraine (FHM) by infantile onset… 
Highly Cited
2003
Highly Cited
2003
Novel mutations in the Na+, K+‐ATPase pump gene ATP1A2 associated with familial hemiplegic migraine and benign familial infantile convulsions
Familial hemiplegic migraine (FHM) is a rare, severe, autosomal dominant subtype of migraine with aura. Up to 75% of FHM families… 
Highly Cited
2002
Highly Cited
2002
Familial hemiplegic migraine mutations increase Ca2+ influx through single human CaV2.1 channels and decrease maximal CaV2.1 current density in neurons
Insights into the pathogenesis of migraine with aura may be gained from a study of human CaV2.1 channels containing mutations… 
Highly Cited
2001
Highly Cited
2001
Delayed cerebral edema and fatal coma after minor head trauma: Role of the CACNA1A calcium channel subunit gene and relationship with familial hemiplegic migraine
Trivial head trauma may be complicated by severe, sometimes even fatal, cerebral edema and coma occurring after a lucid interval… 
Highly Cited
1999
Highly Cited
1999
Functional Consequences of Mutations in the Human α1A Calcium Channel Subunit Linked to Familial Hemiplegic Migraine
Mutations in α1A, the pore-forming subunit of P/Q-type calcium channels, are linked to several human diseases, including familial… 
Highly Cited
1996
Highly Cited
1996
Familial Hemiplegic Migraine and Episodic Ataxia Type-2 Are Caused by Mutations in the Ca2+ Channel Gene CACNL1A4
Highly Cited
1993
Highly Cited
1993
A gene for familial hemiplegic migraine maps to chromosome 19
Familial hemiplegic migraine is an autosomal dominant disorder of unknown pathogenesis in which the migrainous attacks are marked… 
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