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Familial Cerebral Amyloid Angiopathy

Known as: Cerebral Amyloid Angiopathy, Familial, Autosomal Dominant Cerebrovascular Amyloidosis, HCHWA 
A familial disorder marked by AMYLOID deposits in the walls of small and medium sized blood vessels of CEREBRAL CORTEX and MENINGES.
National Institutes of Health

Papers overview

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Highly Cited
2004
Highly Cited
2004
The E693Q mutation in the amyloid beta precursor protein (APP) leads to cerebral amyloid angiopathy (CAA), with recurrent… Expand
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Highly Cited
2002
Highly Cited
2002
: Amyloid beta protein (A beta) deposition in the cerebral arterial and capillary walls is one of the major characteristics of… Expand
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Highly Cited
1996
Highly Cited
1996
Cerebrovascular amyloid beta-protein (Abeta) deposition is a pathological feature of several related disorders including… Expand
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Highly Cited
1995
Highly Cited
1995
We have studied the effects of amyloid β-peptide analogues on the activity of tissue-type plasminogen activator (t-PA) in vitro… Expand
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Highly Cited
1992
Highly Cited
1992
Deposition of extraneuronal fibrils that assemble from the 39-43 residue beta/A4 amyloid protein is one of the earliest… Expand
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Highly Cited
1991
Highly Cited
1991
beta-Amyloid (A beta) deposition in fibril form is the central event in a number of diseases, including Alzheimer's disease (AD… Expand
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Highly Cited
1990
Highly Cited
1990
Human hereditary cerebral hemorrhage with amyloidosis of the Dutch type (HCHWA-D), an autosomal dominant form of cerebral amyloid… Expand
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Highly Cited
1990
Highly Cited
1990
Two families have been described previously with the features of an autosomal dominant familial cerebral amyloid angiopathy with… Expand
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Highly Cited
1987
Highly Cited
1987
Amyloid deposition is a prominent feature of a number of brain disorders, in which amyloid fibrils are found within blood vessel… Expand
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Highly Cited
1982
Highly Cited
1982
Eleven patients belonging to two generations of a Dutch family with cerebral and cerebellar haemorrhage, haemorrhagic infarction… Expand
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