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Factor VII-targeting Immunoconjugate Protein ICON-1

Known as: ICON-1, FVII Modified Conjugate ICON-1, VII-Fc Fusion Protein ICON-1 
A human immunoconjugate (ICON) fusion protein composed of a modified version of human factor VII (FVII) which targets tissue factor (TF) that is… Expand
National Institutes of Health

Papers overview

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2017
2017
Targeting cancer stem cell (CSC) represents a promising therapeutic approach as it can potentially fight cancer at its root. The… Expand
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2016
2016
BACKGROUND As a consequence of population ageing, the number of older patients presenting with acute coronary syndrome (ACS) is… Expand
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2013
2013
Abstract. As part of a broader effort to develop next-generation models for numerical weather prediction and climate applications… Expand
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2011
2011
Background:The purpose of this study was to test a novel, dual tumour vascular endothelial cell (VEC)- and tumour cell-targeting… Expand
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2011
2011
Congenital factor VII (FVII) deficiency is a rare autosomal recessive bleeding disorder. Its clinical manifestation and… Expand
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2006
2006
BACKGROUND Nonsense mutations in coagulation factor (F) VII potentially cause a lethal hemorrhagic diathesis. Readthrough of… Expand
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2004
2004
Inherited factor (F)VII deficiency is rare in most populations but relatively common in Israel. The aim of this study was to… Expand
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2002
2002
Activated Factor VII (FVIIa) is a vitamin-K-dependent serine protease that initiates blood clotting after interacting with its… Expand
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1999
1999
We investigated the mechanisms responsible for severe factor VII (FVII) deficiency in homozygous Italian patients with either… Expand
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1994
1994
The blood coagulation cascade is initiated when vessel injury allows factor VII (FVII) to form a complex with tissue factor (TF… Expand
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