FYN gene

Known as: SRC-LIKE KINASE, MGC45350, FYN ONCOGENE RELATED TO SRC, FGR, YES 
This gene plays a role in the regulation of cell growth and proliferation.
National Institutes of Health

Papers overview

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Highly Cited
2014
Highly Cited
2014
Peripheral T cell lymphomas (PTCLs) are a heterogeneous and poorly understood group of non-Hodgkin lymphomas. Here we combined… (More)
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Highly Cited
2005
Highly Cited
2005
Glucocorticoids (GCs) are effective immunosuppressive agents and mediate well-defined transcriptional effects via GC receptors… (More)
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Highly Cited
2005
Highly Cited
2005
Human amyloid precursor protein (hAPP) transgenic mice with high levels of amyloid-beta (Abeta) develop behavioral deficits that… (More)
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Highly Cited
2005
Highly Cited
2005
Nonreceptor protein tyrosine kinases of the Src family regulate the survival, proliferation, differentiation, and motility of… (More)
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Review
2004
Review
2004
The function of the Src-family kinases (SFKs) Lck and Fyn in T cells has been intensively studied over the past 15 years. Animal… (More)
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Highly Cited
2001
Highly Cited
2001
We analyzed the role of Fyn tyrosine kinase in CNS myelination by using fyn(-/-) null mutant mice, which express no Fyn protein… (More)
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Highly Cited
1999
Highly Cited
1999
In the central nervous system, myelination of axons occurs when oligodendrocyte progenitors undergo terminal differentiation and… (More)
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Highly Cited
1997
Highly Cited
1997
To examine the physiological role of the Fyn tyrosine kinase in neurons, we generated transgenic mice that expressed a fyn cDNA… (More)
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Highly Cited
1996
Highly Cited
1996
Lck, a Src family tyrosine kinase, transduces signals important for the development of alphabeta and gammadelta T cells. However… (More)
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Highly Cited
1995
Highly Cited
1995
MOUSE embryos lacking Csk, a negative regulator of Src family kinases, exhibit defects in neurulation and die at mid-gestation1,2… (More)
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