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FR 901464

Known as: FR-901464, FR901464 
 
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
Mining the genome sequence of Burkholderia thailandensis MSMB43 revealed a cryptic biosynthetic gene cluster resembling that of… Expand
Highly Cited
2011
Highly Cited
2011
Two unrelated bacterial natural products, FR901464 and pladienolide B, have previously been shown to have significant antitumor… Expand
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Highly Cited
2011
Highly Cited
2011
FR901464, a natural product isolated from a bacterium source, activates a reporter gene, inhibits pre-mRNA splicing, and shows… Expand
2010
2010
Spliceostatin A (SSA) is a methylated derivative of an antitumor natural product FR901464, which specifically binds and inhibits… Expand
Highly Cited
2009
Highly Cited
2009
FR901464 is a potent antitumor natural product that binds to the splicing factor 3b complex and inhibits pre-mRNA splicing. Its… Expand
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Highly Cited
2008
Highly Cited
2008
We report the design and highly enantioselective synthesis of a potent analogue of the spliceosome inhibitor FR901464, based on a… Expand
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Highly Cited
2007
Highly Cited
2007
The removal of intervening sequences from transcripts is catalyzed by the spliceosome, a multicomponent complex that assembles on… Expand
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Highly Cited
2001
Highly Cited
2001
The natural product FR901464 (1) was isolated by the Fujisawa Pharmaceutical Co. and shown to have intriguing biological… Expand
Highly Cited
1997
Highly Cited
1997
No. 2663. The taxonomy, fermentation, isolation and physico-chemical properties and biological activities have been described in… Expand
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Highly Cited
1996
Highly Cited
1996
FR901463, FR901464 and FR901465, novel antitumor substances, were isolated from the fermentation broth of Pseudomonas sp. No… Expand
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