FR 901464

Known as: FR-901464, FR901464 
 

Topic mentions per year

Topic mentions per year

1996-2016
02419962016

Papers overview

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2014
2014
Spliceostatins are potent spliceosome inhibitors biosynthesized by a hybrid nonribosomal peptide synthetase-polyketide synthase… (More)
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2013
2013
Mining the genome sequence of Burkholderia thailandensis MSMB43 revealed a cryptic biosynthetic gene cluster resembling that of… (More)
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2011
2011
Two unrelated bacterial natural products, FR901464 and pladienolide B, have previously been shown to have significant antitumor… (More)
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2010
2010
Spliceostatin A (SSA) is a methylated derivative of an antitumor natural product FR901464, which specifically binds and inhibits… (More)
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2009
2009
FR901464 is a potent antitumor natural product that binds to the splicing factor 3b complex and inhibits pre-mRNA splicing. Its… (More)
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2008
2008
We report the design and highly enantioselective synthesis of a potent analogue of the spliceosome inhibitor FR901464, based on a… (More)
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Highly Cited
2007
Highly Cited
2007
The removal of intervening sequences from transcripts is catalyzed by the spliceosome, a multicomponent complex that assembles on… (More)
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2007
2007
FR901464 is a potent anticancer natural product that lowers the mRNA levels of oncogenes and tumor suppressor genes. In this… (More)
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1996
1996
FR901463, FR901464 and FR901465, novel antitumor substances, were isolated from the fermentation broth of Pseudomonas sp. No… (More)
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1996
1996
New antitumor substances, FR901463, FR901464 and FR901465 were isolated from the culture broth of a bacterium of Pseudomonas sp… (More)
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