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FR 901464

Known as: FR-901464, FR901464 
 
National Institutes of Health

Papers overview

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2014
2014
Sudemycin E is an analog of the pre-messenger RNA splicing modulator FR901464 and its derivative spliceostatin A. Sudemycin E… Expand
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2013
2013
Mining the genome sequence of Burkholderia thailandensis MSMB43 revealed a cryptic biosynthetic gene cluster resembling that of… Expand
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Highly Cited
2011
Highly Cited
2011
Two unrelated bacterial natural products, FR901464 and pladienolide B, have previously been shown to have significant antitumor… Expand
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2011
2011
FR901464, a natural product isolated from a bacterium source, activates a reporter gene, inhibits pre-mRNA splicing, and shows… Expand
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2010
2010
Spliceostatin A (SSA) is a methylated derivative of an antitumor natural product FR901464, which specifically binds and inhibits… Expand
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2009
2009
FR901464 is a potent antitumor natural product that binds to the splicing factor 3b complex and inhibits pre-mRNA splicing. Its… Expand
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2008
2008
We report the design and highly enantioselective synthesis of a potent analogue of the spliceosome inhibitor FR901464, based on a… Expand
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Highly Cited
2007
Highly Cited
2007
The removal of intervening sequences from transcripts is catalyzed by the spliceosome, a multicomponent complex that assembles on… Expand
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Highly Cited
1996
Highly Cited
1996
FR901463, FR901464 and FR901465, novel antitumor substances, were isolated from the fermentation broth of Pseudomonas sp. No… Expand
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1996
1996
New antitumor substances, FR901463, FR901464 and FR901465 were isolated from the culture broth of a bacterium of Pseudomonas sp… Expand
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