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FP-1039

Known as: FGF Receptor Antagonist HGS1036, GSK3052230, HGS1036 
A soluble fusion protein consisting of the extracellular domain of human fibroblast growth factor receptor 1 (FGFR1) fused to the Fc portion of human… Expand
National Institutes of Health

Papers overview

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2019
2019
Background Fibroblast growth factors (FGFs) have a fundamental role in cancer. Sequestering FGFs with GSK3052230 (FP-1039) blocks… Expand
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2016
2016
BACKGROUND Fibroblast growth factors (FGFs) play important roles in multiple cancers by supporting tumor growth and angiogenesis… Expand
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2016
2016
Fibroblast growth factor (FGF) ligand-dependent signaling has a fundamental role in cancer development and tumor maintenance… Expand
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2014
2014
Proceedings: AACR Annual Meeting 2014; April 5-9, 2014; San Diego, CA Fibroblast growth factor (FGF) ligand-dependent signaling… Expand
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Highly Cited
2013
Highly Cited
2013
A soluble FGF receptor trap effectively inhibits tumor growth in the absence of toxicity. Treating Cancer by Design The… Expand
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Highly Cited
2011
Highly Cited
2011
Purpose: We previously reported that a fibroblast growth factor (FGF) receptor (FGFR) signaling pathway drives growth of lung… Expand
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2010
2010
Proceedings: AACR 101st Annual Meeting 2010‐‐ Apr 17‐21, 2010; Washington, DC Endometrial cancer is the most common… Expand
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2010
2010
Figure 1. Targeting the FGF/FGFR Pathway with FP-1039. The FGF axis contains 4 FGF receptors with multiple splice forms and 22… Expand
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2007
2007
B55 FP-1039 is a soluble fusion protein consisting of the extracellular domain of human fibroblast growth factor receptor 1c… Expand
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