FAQ

FOXP3 wt Allele

Known as: PIDX, XPID, Forkhead Box P3 wt Allele 
Human FOXP3 wild-type allele is located in the vicinity of Xp11.23 and is approximately 14 kb in length. This allele, which encodes forkhead box… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1948-2017
05101519482016

Related topics

Related topics

3 relations
Homo sapiensTranscriptional Regulationdna binding

Related mentions per year

Related mentions per year

1937-2018
19401960198020002020
FOXP3 wt Allele
dna binding
Homo sapiens
Transcriptional Regulation

Papers overview

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Highly Cited
2007
Highly Cited
2007
CD25 deficiency causes an immune dysregulation, polyendocrinopathy, enteropathy, X-linked-like syndrome, and defective IL-10 expression from CD4 lymphocytes.
BACKGROUND Immune dysregulation, polyendocrinopathy, enteropathy, X-linked (IPEX) results in systemic autoimmunity from birth and… (More)
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Highly Cited
2007
Highly Cited
2007
Severe food allergy as a variant of IPEX syndrome caused by a deletion in a noncoding region of the FOXP3 gene.
BACKGROUND & AIMS Immune dysregulation, polyendocrinopathy, enteropathy, X-linked (IPEX; OMIM 304930) syndrome is a congenital… (More)
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Highly Cited
2007
Highly Cited
2007
FOXP3 is a homo-oligomer and a component of a supramolecular regulatory complex disabled in the human XLAAD/IPEX autoimmune disease.
We have found that FOXP3 is an oligomeric component of a large supramolecular complex. Certain FOXP3 mutants with single amino… (More)
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2007
2007
Prior exercise increases phosphorylation of Akt substrate of 160 kDa (AS160) in rat skeletal muscle.
The main purpose of this study was to determine whether the increased glucose transport (GT) found immediately postexercise (IPEX… (More)
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Highly Cited
2006
Highly Cited
2006
Defective regulatory and effector T cell functions in patients with FOXP3 mutations.
The autoimmune disease immune dysregulation, polyendocrinopathy, enteropathy, X-linked (IPEX) is caused by mutations in the… (More)
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Highly Cited
2006
Highly Cited
2006
Analysis of FOXP3 reveals multiple domains required for its function as a transcriptional repressor.
Foxp3 has been shown to be both necessary and sufficient for the development and function of naturally arising CD4+ CD25… (More)
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Highly Cited
2001
Highly Cited
2001
The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3
IPEX is a fatal disorder characterized by immune dysregulation, polyendocrinopathy, enteropathy and X-linked inheritance (MIM… (More)
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Highly Cited
2001
Highly Cited
2001
X-linked neonatal diabetes mellitus, enteropathy and endocrinopathy syndrome is the human equivalent of mouse scurfy
To determine whether human X-linked neonatal diabetes mellitus, enteropathy and endocrinopathy syndrome (IPEX; MIM 304930) is the… (More)
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Highly Cited
2001
Highly Cited
2001
A rare polyadenylation signal mutation of the FOXP3 gene (AAUAAA→AAUGAA) leads to the IPEX syndrome
The mouse scurfy gene, Foxp3, and its human orthologue, FOXP3, which maps to Xp11.23–Xq13.3, were recently identified by… (More)
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Highly Cited
2000
Highly Cited
2000
JM2, encoding a fork head-related protein, is mutated in X-linked autoimmunity-allergic disregulation syndrome.
X-linked autoimmunity-allergic disregulation syndrome (XLAAD) is an X-linked recessive immunological disorder characterized by… (More)
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