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FNIP1 gene

Known as: KIAA1961, FNIP1, folliculin interacting protein 1 
 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
Mutations of the gene FNIP1 associated with a syndromic autosomal recessive immunodeficiency with cardiomyopathy and pre‐excitation syndrome
AMPK (adenosine monophosphate-activated protein kinase) is phosphorylated (AMPK-P) in response to low energy through allosteric… Expand
2020
2020
miR-208b modulating skeletal muscle development and energy homoeostasis through targeting distinct targets
ABSTRACT Embryonic and neonatal skeletal muscles grow via the proliferation and fusion of myogenic cells, whereas adult skeletal… Expand
2019
2019
Folliculin Interacting Protein 1 Maintains Metabolic Homeostasis during B Cell Development by Modulating AMPK, mTORC1, and TFE3
Key Points Fnip1 is required for pre–B cell development/survival independent of p53 and Bcl-xL. Fnip1 is required for optimal… Expand
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Review
2019
Review
2019
Review for "Mutations of the gene FNIP1 associated with a syndromic autosomal recessive immunodeficiency with cardiomyopathy and pre‐excitation syndrome"
 
2018
2018
Loss of Fnip1 alters kidney developmental transcriptional program and synergizes with TSC1 loss to promote mTORC1 activation and renal cyst formation
Birt-Hogg-Dube’ Syndrome (BHDS) is a rare genetic disorder in humans characterized by skin hamartomas, lung cysts, pneumothorax… Expand
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2017
2017
Dihydromyricetin prevents obesity-induced slow-twitch-fiber reduction partially via FLCN/FNIP1/AMPK pathway.
Obesity is often accompanied by decreases in the proportion of skeletal muscle slow-twitch fibers and insulin sensitivity… Expand
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2016
2016
Abstract 4543: Substrate trapping proteomics reveals novel mechanism for regulation of mTORC1 signaling by βTrCP-FNIP1/2-FLCN axis
Defining the full complement of substrates for each ubiquitin ligase remains an important challenge. Improvements in mass… Expand
Highly Cited
2015
Highly Cited
2015
Folliculin-interacting proteins Fnip1 and Fnip2 play critical roles in kidney tumor suppression in cooperation with Flcn
Significance The role of FLCN as a tumor suppressor in kidney cancer has been well documented, whereas the functional roles of… Expand
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Highly Cited
2008
Highly Cited
2008
Identification and characterization of a novel folliculin-interacting protein FNIP2.
Birt-Hogg-Dube' syndrome characterized by increased risk for renal neoplasia is caused by germline mutations in the BHD/FLCN gene… Expand
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Highly Cited
2006
Highly Cited
2006
Folliculin encoded by the BHD gene interacts with a binding protein, FNIP1, and AMPK, and is involved in AMPK and mTOR signaling
Birt–Hogg–Dubé syndrome, a hamartoma disorder characterized by benign tumors of the hair follicle, lung cysts, and renal… Expand
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