FNDC5 gene

Known as: fibronectin type III domain containing 5, IRISIN, FNDC5 
 
National Institutes of Health

Papers overview

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Highly Cited
2014
Highly Cited
2014
Irisin was identified as a myokine secreted by contracting skeletal muscle, possibly mediating some exercise health benefits via… (More)
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Highly Cited
2013
Highly Cited
2013
Exercise can improve cognitive function and has been linked to the increased expression of brain-derived neurotrophic factor… (More)
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Highly Cited
2013
Highly Cited
2013
Exercise provides clear beneficial effects for the prevention of numerous diseases. However, many of the molecular events… (More)
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Highly Cited
2013
Highly Cited
2013
Recently, contradictory findings have been reported concerning the function of irisin and its precursor gene, skeletal muscle… (More)
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Highly Cited
2013
Highly Cited
2013
CONTEXT Recently irisin (encoded by Fndc5 gene) has been reported to stimulate browning and uncoupling protein 1 expression in sc… (More)
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Highly Cited
2013
Highly Cited
2013
AIMS Irisin has been identified as a novel myokine that drives brown-fat-like conversion of white adipose tissue. In this cross… (More)
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Highly Cited
2012
Highly Cited
2012
OBJECTIVE In mouse, PGC1-α overexpression in muscle stimulates an increase in expression of FNDC5, a membrane protein that is… (More)
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Highly Cited
2012
Highly Cited
2012
Exercise benefits a variety of organ systems in mammals, and some of the best-recognized effects of exercise on muscle are… (More)
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Highly Cited
2012
Highly Cited
2012
Arising from P. Boström et al. 481, 463–468 (2012)10.1038/nature10777Boström et al. report that exercise training induces the… (More)
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Highly Cited
2012
Highly Cited
2012
BACKGROUND Exercise-induced increase in peroxisome proliferator-activated receptor-γ coactivator-1α (PGC-1α) expression has been… (More)
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