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FLT3 NP_004110.2:p.D835X
Known as:
Stem Cell Tyrosine Kinase 1 D835X
, FLT3 Asp835Xxx
, NP_004110.2:p.Asp835Xxx
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A change in the amino acid residue at position 835 in the receptor-type tyrosine-protein kinase FLT3 protein where asparagine has been replaced by…
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National Institutes of Health
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Papers overview
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2019
2019
Neue FLT3 Inhibitoren bei der AML und andere Targets
Carola Göring
InFo Hämatologie + Onkologie
2019
Corpus ID: 186323957
Was kommt nach Midostaurin? Derzeit werden bei der FLT3-mutierten akuten myeloischen Leukämie (FLT3-AML) Inhibitoren der nächsten…
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2016
2016
FLT3 Splice Variant (FLT3Va) As a Potential Immunotherapeutic Target in Patients with Acute Myeloid Leukemia (AML)
Sophia Adamia
,
J. Nemeth
,
+14 authors
J. Griffin
Blood
2016
Corpus ID: 78712652
Alternative pre-mRNA splicing (AS) is a normal epigenetic phenomenon, a key regulator of gene expression, yields multiple…
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Review
2014
Review
2014
Telomere Length Is Associated with Specific Mutations and Mutation Classes in Patients with Acute Myeloid Leukemia
J. Watts
,
B. Dumitriu
,
+9 authors
M. Tallman
2014
Corpus ID: 208436238
It is unknown if telomere length (TL) is associated with clinical outcome or molecular profile in acute myeloid leukemia (AML…
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Review
2013
Review
2013
Efficacy and resistance of molecularly targeted therapy for myeloid malignancies FLT 3 inhibitors for acute myeloid leukemia : a review of their efficacy and mechanisms of resistance
M. Grunwald
,
M. Levis
2013
Corpus ID: 207886012
Since the Food and Drug Administration approval of imatinib for treatment of chronic myeloid leukemia in 2001, tyrosine kinase…
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2010
2010
[FLT3 gene mutation and its prognostic implication in patients with acute leukemia.].
Zhonghua xue ye xue za zhi = Zhonghua xueyexue…
2010
Corpus ID: 31980282
OBJECTIVE To evaluate the prevalence of FLT3 mutation in different subtypes of acute leukemia (AL) patients diagnosed by WHO…
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2010
2010
The role of FLT3 in sole trisomy 8 acute myeloid leukemia.
A. Block
,
A. Groman
,
+7 authors
M. Wetzler
2010
Corpus ID: 74695708
6562 Background: FLT3 (fms-related tyrosine kinase 3) with internal tandem duplication (ITD) is a known adverse prognostic factor…
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2010
2010
Méthodes de traitement de maladies prolifératives
Robert E. Corringham
2010
Corpus ID: 132021427
La presente invention concerne des procedes d'administration de N -(5- tert -butyl-isoxazol-3-yl)- N '-{4-[7- (2-morpholin-4-yl…
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2009
2009
Untersuchungen zur Rolle der mutierten Rezeptor-Tyrosinkinase FLT3 bei der Leukämogenese mit Hilfe humaner und muriner Transplantationsmodelle [Mus musculus (Linnaeus, 1758)]
Birte Niebuhr
2009
Corpus ID: 82319988
FLT3 ist eines der am haufigsten mutierten Gene in akuten Leukamien. Es kodiert fur eine Rezeptor-Tyrosinkinase, die durch ihre…
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2008
2008
Hématologie maligne
N. Mounier
ONCOLOGIE
2008
Corpus ID: 45686597
En hématologie maligne, les scoops sont, en général, réservés au congrès de l’ASH en décembre, mais l’ASCO, en juin, fournit une…
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2004
2004
FLT3 Mutations in Normal Karyotype Acute Myeloid Leukemia in First Complete Remission Treated with Autologous Peripheral Blood Stem Cell Transplantation.
G. Yoshimoto
,
K. Nagafuji
,
+7 authors
M. Harada
2004
Corpus ID: 208385338
Two types of activating FLT3 mutations have been described in AML. FLT3/ITDs can be detected in 20% to 30% of patients with AML…
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