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FLT1 protein, human

Known as: FLT1, VEGFR, Tyrosine-Protein Kinase FRT 
Vascular endothelial growth factor receptor 1 (1338 aa, ~151 kDa) is encoded by the human FLT1 gene. This protein is involved in angiogenesis… 
National Institutes of Health

Related topics

Related topics

33 relations
Angiogenesis PathwayAngiogenic ProcessCediranib MaleateCell Differentiation process

Broader (1)

Vascular Endothelial Growth Factor Receptor-1

Papers overview

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Highly Cited
2016
Highly Cited
2016
Predictive Value of the sFlt-1:PlGF Ratio in Women with Suspected Preeclampsia.
BACKGROUND The ratio of soluble fms-like tyrosine kinase 1 (sFlt-1) to placental growth factor (PlGF) is elevated in pregnant… 
Highly Cited
2006
Highly Cited
2006
Soluble endoglin and other circulating antiangiogenic factors in preeclampsia.
BACKGROUND Alterations in circulating soluble fms-like tyrosine kinase 1 (sFlt1), an antiangiogenic protein, and placental growth… 
Review
2005
Review
2005
The vascular endothelial growth factor (VEGF)/VEGF receptor system and its role under physiological and pathological conditions.
The VEGF (vascular endothelial growth factor) family and its receptors are essential regulators of angiogenesis and vascular… 
Highly Cited
2003
Highly Cited
2003
Role of PlGF in the intra- and intermolecular cross talk between the VEGF receptors Flt1 and Flk1
Therapeutic angiogenesis is likely to require the administration of factors that complement each other. Activation of the… 
Highly Cited
2002
Highly Cited
2002
ZD6474 inhibits vascular endothelial growth factor signaling, angiogenesis, and tumor growth following oral administration.
ZD6474 [N-(4-bromo-2-fluorophenyl)-6-methoxy-7-[(1-methylpiperidin-4-yl)methoxy]quinazolin-4-amine]is a potent, p.o. active, low… 
Review
2000
Review
2000
The molecular basis of lung morphogenesis
Highly Cited
1998
Highly Cited
1998
Flt-1 lacking the tyrosine kinase domain is sufficient for normal development and angiogenesis in mice.
Receptor tyrosine kinases Flt-1 and Flk-1/KDR, and their ligand, the vascular endothelial growth factor (VEGF), were shown to be… 
Highly Cited
1996
Highly Cited
1996
Migration of human monocytes in response to vascular endothelial growth factor (VEGF) is mediated via the VEGF receptor flt-1.
Treatment of human monocytes with vascular endothelial growth factor (VEGF) isolated from tumor cell supernatants was reported to… 
Highly Cited
1994
Highly Cited
1994
Different signal transduction properties of KDR and Flt1, two receptors for vascular endothelial growth factor.
Highly Cited
1992
Highly Cited
1992
The fms-like tyrosine kinase, a receptor for vascular endothelial growth factor.
The fms-like tyrosine kinase (Flt) is a transmembrane receptor in the tyrosine kinase family. Expression of flt complementary DNA… 
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