FAQ

FKBP8 protein, human

Known as: FK506-Binding Protein 8, Rotamase, FKBP38 protein, human 
Peptidyl-prolyl cis-trans isomerase FKBP8 (412 aa, ~45 kDa) is encoded by the human FKBP8 gene. This protein is involved in immunoregulation, protein… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1990-2016
01219902016

Related topics

Related topics

4 relations
Enzyme GeneFKBP8 geneIsomerase Gene

Broader (1)

Tacrolimus Binding Proteins

Related mentions per year

Related mentions per year

1978-2018
197019801990200020102020
FKBP8 protein, human
Tacrolimus Binding Proteins
Enzyme Gene
FKBP8 gene
Isomerase Gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2014
Review
2014
Osteogenesis imperfecta due to mutations in non-collagenous genes: lessons in the biology of bone formation.
PURPOSE OF REVIEW Osteogenesis imperfecta or 'brittle bone disease' has mainly been considered a bone disorder caused by collagen… (More)
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2007
2007
Multimer formation by FKBP-12: roles for cysteine 23 and phenylalanine 36.
FKBP-12 mediates the immunosuppressive actions of FK506 and rapamycin, and modulates the activities of the ryanodine, IP3 and… (More)
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Review
2005
Review
2005
'Nature-inspired' drug-protein complexes as inhibitors of Abeta aggregation.
Protein-protein interactions are a regulatory mechanism for a number of physiological and pathological cellular processes… (More)
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Highly Cited
2002
Highly Cited
2002
Active site residues of cyclophilin A are crucial for its signaling activity via CD147.
Cyclophilin A (CyPA), a ubiquitously distributed intracellular protein, is a peptidylprolyl cis-trans-isomerase and the major… (More)
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2000
2000
Postischemic changes in the immunophilin FKBP12 in the rat brain.
An immunosuppressant tacrolimus (FK506) protects against neuronal damage following cerebral ischemia. On the other hand, the… (More)
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1996
1996
Identification and characterization of Schistosoma mansoni p17.7, a cyclophilin.
Antibodies affinity purified against tegumental components of schistosomula were used to screen a Schistosoma mansoni lambda gt11… (More)
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1995
1995
The 59 kDa FK506-binding protein, a 90 kDa heat shock protein binding immunophilin (FKBP59-HBI), is associated with the nucleus, the cytoskeleton and mitotic apparatus.
FKBP59-HBI, a 59 kDa FK506 binding protein which binds the 90 kDa heat shock protein hsp90 and thus is a heat shock protein… (More)
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Review
1992
Review
1992
Cyclosporin A. Mode of action and effects on bone and joint tissues.
Cyclosporin A is an established immunomodulatory agent with an increasing number of clinical applications. Although its precise… (More)
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Highly Cited
1990
Highly Cited
1990
Structure and expression of cytosolic cyclophilin/peptidyl-prolyl cis-trans isomerase of higher plants and production of active tomato cyclophilin in Escherichia coli.
cDNA clones encoding proteins of approximately 18 kDa in which 83% of the amino acids are conserved relative to the published… (More)
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1990
1990
Inhibition of FKBP rotamase activity by immunosuppressant FK506: twisted amide surrogate.
The immunosuppressive agents cyclosporin A and FK506 inhibit the transcription of early T cell activation genes. The binding… (More)
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