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FKBP8 protein, human

Known as: FK506-Binding Protein 8, Rotamase, FKBP38 protein, human 
Peptidyl-prolyl cis-trans isomerase FKBP8 (412 aa, ~45 kDa) is encoded by the human FKBP8 gene. This protein is involved in immunoregulation, protein… Expand
National Institutes of Health

Papers overview

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Review
2014
Review
2014
Purpose of review Osteogenesis imperfecta or ’brittle bone disease’ has mainly been considered a bone disorder caused by collagen… Expand
Review
2008
Review
2008
Ascomycin and FK506 are powerful calcium‐dependent serine/threonine protein phosphatase (calcineurin [CaN], protein phosphatase… Expand
Review
2000
Review
2000
  • F. Dumont
  • Current medicinal chemistry
  • 2000
  • Corpus ID: 25221758
The macrolactam natural product, FK506 (Tacrolimus), acts as a powerful and clinically useful immnosuppressant through disruption… Expand
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Highly Cited
1997
Highly Cited
1997
The human rotamase or peptidyl-prolyl cis-trans isomerase Pin1 is a conserved mitotic regulator essential for the G2/M transition… Expand
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Highly Cited
1994
Highly Cited
1994
Cyclophilin (CyP), a protein with peptidyl-prolyl cis-trans isomerase (rotamase) activity, is the specific cellular target of… Expand
Highly Cited
1992
Highly Cited
1992
Immunophilins, a family of proteins that exhibit rotamase (peptidyl-prolyl cis-trans isomerase) activity in vitro, are expressed… Expand
Highly Cited
1992
Highly Cited
1992
In the rabbit, a p59 protein included in the untransformed, non-DNA binding, "8-9S," steroid receptor complexes binds heat shock… Expand
Review
1992
Review
1992
Cyclosporin A is an established immunomodulatory agent with an increasing number of clinical applications. Although its precise… Expand
Highly Cited
1990
Highly Cited
1990
cDNA clones encoding proteins of approximately 18 kDa in which 83% of the amino acids are conserved relative to the published… Expand
Highly Cited
1990
Highly Cited
1990
The immunosuppressive agents cyclosporin A and FK506 inhibit the transcription of early T cell activation genes. The binding… Expand