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FK 888

Known as: FK-888, FK888, L-Alaninamide, trans-4-hydroxy-1-((1-methyl-1H-indol-3-yl)carbonyl)-L-prolyl-N-methyl-3-(2-naphthalenyl)-N-(phenylmethyl)- 
National Institutes of Health

Related topics

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2 relations

Broader (2)

DipeptidesIndoles

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2006
2006
NK2 Receptor-Mediated Spontaneous Phasic Contractions in Normal and Ulcerative Colitis Human Sigmoid Colon
Human colonic circular muscle produces spontaneous phasic contractions that are reduced in ulcerative colitis. How the… 
Highly Cited
2000
Highly Cited
2000
Gq-linked NK(2) receptors mediate neurally induced contraction of human sigmoid circular smooth muscle.
BACKGROUND & AIMS Because tachykinins have been identified as neurotransmitters in the guinea pig colon and human ileum, we… 
Highly Cited
1999
Highly Cited
1999
Functional neurokinin NK-1 receptor expression in rat peritoneal mast cells
Objective and Design: Recently, Ogawa et al. [17] reported that the peritoneal mast cells (PMCs) of rats can release histamine by… 
1999
1999
Receptor subtypes involved in tachykinin-mediated edema formation☆
1999
1999
Correlation between binding characteristics and functional antagonism in human glioma cells by tachykinin NK1 receptor antagonists.
1999
1999
Intragastric Capsaicin Stimulates Motility of Upper Gut and Proximal Colon via Distinct Pathways in Conscious Dogs
The aim of the present study was to investigatethe effect and mechanism of action of intragastric andintraduodenal capsaicin on… 
Highly Cited
1997
Highly Cited
1997
In vitro and in vivo predictors of the anti-emetic activity of tachykinin NK1 receptor antagonists.
1996
1996
Involvement of NK2 receptors rather than NK1 receptors in bronchial hyperresponsiveness induced by allergic reaction in guinea‐pigs
1 In this study, the role of neuropeptides in antigen‐induced bronchoconstriction and bronchial responsiveness in guinea‐pigs was… 
1994
1994
Comparison of tachykinin NK1 receptors in human IM9 and U373 MG cells, using antagonist (FK888, (+/-)-CP-96,345, and RP 67580) binding.
1993
1993
Effects of an NK1 receptor antagonist, FK888, on constriction and plasma extravasation induced in guinea pig airway by neurokinins and capsaicin.
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