FGFR4 Inhibitor H3B-6527

Known as: H3B 6527, H3B6527, H3B-6527 
An orally bioavailable inhibitor of human fibroblast growth factor receptor 4 (FGFR4), with potential antineoplastic activity. Upon administration… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1995-2016
01219952016

Papers overview

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2017
2017
Activation of the fibroblast growth factor receptor FGFR4 by FGF19 drives hepatocellular carcinoma (HCC), a disease with few, if… (More)
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2016
2016
PURPOSE The purpose of this study is to investigate the role of fibroblast growth factor receptor 4 (FGFR4) polymorphism in… (More)
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2016
2016
Fibroblast growth factor receptor 4 (FGFR4) is a transmembrane receptor with ligand-induced tyrosine kinase activity and is… (More)
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2010
2010
BACKGROUND A single-nucleotide polymorphism (SNP) in the FGFR4 gene is associated with poor prognosis in solid tumors. A recent… (More)
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2009
2009
The genotype analysis of the Gly and Arg allele at codon 388 of fibroblast growth factor receptor-4 (FGFR4) gene was evaluated… (More)
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2007
2007
BACKGROUND The increased expression of the fibroblast growth factor receptor 4 (FGFR4) has been identified in many human cancers… (More)
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1995
1995
We have identified a novel FGF receptor, Z-FGFR4, in zebrafish embryos. Z-FGFR4 is closely related to both chicken FREK (Marcelle… (More)
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