FAQ

FGF23 protein, human

Known as: Tumor-Derived Hypophosphatemia-Inducing Factor, Phosphatonin, Tumor-Derived Hypophosphatemia Inducing Factor 
Fibroblast growth factor 23 (251 aa, ~28 kDa) is encoded by the human FGF23 gene. This protein is involved in inhibition of renal tubular phosphate… (More)

Topic mentions per year

Topic mentions per year

1995-2018
020406019952018

Related topics

Related topics

16 relations
Angiogenic ProcessCell Differentiation processCell Proliferation Regulatory ProcessExtracellular Space
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Broader (1)

fibroblast growth factor 23

Related mentions per year

Related mentions per year

1938-2018
19401960198020002020
FGF23 protein, human
Cell Differentiation process
receptor binding
Extracellular Space
Intercellular Communication Process
heparin binding

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2011
Highly Cited
2011
Fibroblast growth factor 23 and risks of mortality and end-stage renal disease in patients with chronic kidney disease.
CONTEXT A high level of the phosphate-regulating hormone fibroblast growth factor 23 (FGF-23) is associated with mortality in… (More)
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Highly Cited
2009
Highly Cited
2009
Fibroblast growth factor 23 and left ventricular hypertrophy in chronic kidney disease.
BACKGROUND Fibroblast growth factor 23 (FGF-23) is a phosphorus-regulating hormone. In chronic kidney disease (CKD), circulating… (More)
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Highly Cited
2009
Highly Cited
2009
High levels of serum fibroblast growth factor (FGF)-23 are associated with increased mortality in long haemodialysis patients.
BACKGROUND Fibroblast growth factor (FGF)-23, a novel bone-derived phosphaturic factor involved in mineral metabolism, is… (More)
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Highly Cited
2008
Highly Cited
2008
Fibroblast growth factor 23 and mortality among patients undergoing hemodialysis.
BACKGROUND Fibroblast growth factor 23 (FGF-23) is a hormone that increases the rate of urinary excretion of phosphate and… (More)
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Highly Cited
2005
Highly Cited
2005
Fibroblast growth factor-23 mitigates hyperphosphatemia but accentuates calcitriol deficiency in chronic kidney disease.
Hyperphosphatemia, calcitriol deficiency, and secondary hyperparathyroidism (SHPT) are common complications of chronic kidney… (More)
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Highly Cited
2005
Highly Cited
2005
Fibroblast growth factor-23 relationship to dietary phosphate and renal phosphate handling in healthy young men.
The renal handling of inorganic phosphate (Pi) is controlled not only by PTH, but also by hitherto undetermined mechanisms… (More)
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Highly Cited
2004
Highly Cited
2004
FGF-23 is a potent regulator of vitamin D metabolism and phosphate homeostasis.
UNLABELLED We analyzed the effects of an FGF-23 injection in vivo. FGF-23 caused a reduction in serum 1,25-dihydroxyvitamin D by… (More)
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Highly Cited
2004
Highly Cited
2004
Homozygous ablation of fibroblast growth factor-23 results in hyperphosphatemia and impaired skeletogenesis, and reverses hypophosphatemia in Phex-deficient mice.
Fibroblast growth factor-23 (FGF-23), a recently identified molecule that is mutated in patients with autosomal dominant… (More)
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Highly Cited
2003
Highly Cited
2003
Fibroblast growth factor 23 in oncogenic osteomalacia and X-linked hypophosphatemia.
BACKGROUND Mutations in fibroblast growth factor 23 (FGF-23) cause autosomal dominant hypophosphatemic rickets. Clinical and… (More)
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Highly Cited
2003
Highly Cited
2003
Circulating concentration of FGF-23 increases as renal function declines in patients with chronic kidney disease, but does not change in response to variation in phosphate intake in healthy…
BACKGROUND Hyperphosphatemia is a risk factor for the development of several different complications of chronic kidney disease… (More)
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