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The FEZ1/LZTS1 (FEZ1) gene maps to chromosome 8p22 and is frequently altered in human cancer. FEZ1 has been proposed as a… Expand FEZ1/LZTS1 is a tumor suppressor gene located in chromosomal band 8p22, and methylation has been identified as a mechanism for… Expand FEZ1/LZTS1 is a tumor suppressor gene that is frequently altered in human cancers of different histotypes. We have reported… Expand Considerable evidence has accumulated suggesting that cancer has genetic origin, based on the development of genomic alterations… Expand BackgroundCollecting duct carcinoma (CDC) is a rare but very aggressive variant of kidney carcinoma that arises from the… Expand Allelic deletions on the short arm of chromosome 8 (8p) are frequent events in several human malignancies, including oral cancer… Expand FEZ1/LZTS1 is a tumor suppressor gene that maps to chromosome 8p22, a chromosomal region frequently deleted in many human… Expand PURPOSE
The FEZ1/LZTS1 (FEZ1) gene, located on chromosome 8p22 (8p22), was identified recently as a candidate tumor suppressor… Expand The FEZ1/LZTS1 gene maps to chromosome 8p22, a region that is frequently deleted in human tumors. Alterations in FEZ1/LZTS1… Expand PURPOSE
Loss of heterozygosity (LOH) involving the short arm of chromosome 8 (8p) is a common feature of the malignant… Expand