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FERMT3 protein, human

Known as: MIG2-Like Protein, Unc-112-Related Protein 2, Kindlin-3 
Fermitin family homolog 3 (667 aa, ~76 kDa) is encoded by the human FERMT3 gene. This protein plays a role in hematopoietic cell adhesion, migration… Expand
National Institutes of Health

Papers overview

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2015
2015
The bidirectional signaling and hemostatic functions of platelet αIIbβ3 are regulated by kindlin-3 through interactions with the… Expand
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2014
2014
OBJECTIVE Kindlin-3 is a critical supporter of integrin function in platelets. Lack of expression of kindlin-3 protein in… Expand
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2014
2014
The FERM domain containing protein Kindlin-3 has been recognized as a major regulator of integrin function in hematopoietic cells… Expand
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2013
2013
Integrins mediate cell-cell and cell-extracellular matrix attachments. Integrins are signaling receptors because their… Expand
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Highly Cited
2012
Highly Cited
2012
In inflammation, neutrophils and other leukocytes roll along the microvascular endothelium before arresting and transmigrating… Expand
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2012
2012
Background: Kindlin-3 is a novel integrin activator with unclear mechanism. Results: Calpain cleaves Kindlin-3 at Y-373. Cleavage… Expand
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2011
2011
Chemokine/chemoattractant G protein-coupled receptors trigger an inside–out signaling network that rapidly activates integrins, a… Expand
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2010
2010
The integrin αIIbβ3 is a transmembrane (TM) heterodimeric adhesion receptor that exists in equilibrium between resting and active… Expand
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Highly Cited
2010
Highly Cited
2010
Integrin activation is crucial for numerous cellular responses, including cell adhesion, migration, and survival. Recent studies… Expand
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Highly Cited
2009
Highly Cited
2009
Integrin activation is essential for the function of all blood cells, including platelets and leukocytes. The blood cell–specific… Expand
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