FERMT3 protein, human

Known as: MIG2-Like Protein, Unc-112-Related Protein 2, Kindlin-3 
Fermitin family homolog 3 (667 aa, ~76 kDa) is encoded by the human FERMT3 gene. This protein plays a role in hematopoietic cell adhesion, migration… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

2006-2018
051020062018

Papers overview

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2014
2014
The FERM domain containing protein Kindlin-3 has been recognized as a major regulator of integrin function in hematopoietic cells… (More)
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2013
2013
Kindlin-3 is mutated in the rare genetic disorder, leukocyte adhesion deficiency type III, which is characterized by deficient… (More)
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Highly Cited
2012
Highly Cited
2012
In inflammation, neutrophils and other leukocytes roll along the microvascular endothelium before arresting and transmigrating… (More)
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2011
2011
The blood cell-specific kindlin-3 protein is required to activate leukocyte and platelet integrins. In line with this function… (More)
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2011
2011
Chemokine/chemoattractant G protein-coupled receptors trigger an inside-out signaling network that rapidly activates integrins, a… (More)
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2010
2010
Integrin activation is crucial for numerous cellular responses, including cell adhesion, migration, and survival. Recent studies… (More)
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2010
2010
The integrin αIIbβ3 is a transmembrane (TM) heterodimeric adhesion receptor that exists in equilibrium between resting and active… (More)
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Highly Cited
2009
Highly Cited
2009
Integrin activation is essential for the function of all blood cells, including platelets and leukocytes. The blood cell–specific… (More)
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2008
Highly Cited
2008
Integrin-mediated platelet adhesion and aggregation are essential for sealing injured blood vessels and preventing blood loss… (More)
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Highly Cited
2006
Highly Cited
2006
The three Kindlins are a novel family of focal adhesion proteins. The Kindlin-1 (URP1) gene is mutated in Kindler syndrome, the… (More)
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