Skip to search formSkip to main contentSkip to account menu

FERMT3 gene

Known as: Fermitin Family Member 3 Gene, kindlin-3, FERMITIN FAMILY (DROSOPHILA) HOMOLOG 3 
This gene plays a role in cell adhesion in hematopoietic cells.
National Institutes of Health

Related topics

Related topics

6 relations
Cell-Cell Adhesion ProcessFERMT2 geneFERMT3 protein, humanIntegrin Binding

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
Differences in self-association between kindlin-2 and kindlin-3 are associated with differential integrin binding
The integrin family of transmembrane adhesion receptors coordinates complex signaling networks that control the ability of cells… 
2017
2017
Activated &bgr;2 Integrins Restrict Neutrophil Recruitment during Murine Acute Pseudomonal Pneumonia
&NA; Rapid neutrophil recruitment is critical for the efficient clearance of bacterial pathogens from the lungs. Although &bgr;2… 
2017
2017
Expression of kindlin-3 in melanoma cells impedes cell migration and metastasis
ABSTRACT Kindlins are a small family of 4.1-ezrin-radixin-moesin (FERM)-containing cytoplasmic proteins. Kindlin-3 is expressed… 
2015
2015
Interaction of kindlin-3 and β2-integrins differentially regulates neutrophil recruitment and NET release in mice.
Kindlin-3 essentially supports integrin activation in blood cells. Absence of kindlin-3 in humans causes leukocyte adhesion… 
2014
2014
A novel tumor suppressor function of Kindlin-3 in solid cancer
Kindlin-3 (FERMT-3) is known to be central in hemostasis and thrombosis control and its deficiency disrupts platelet aggregation… 
2013
2013
The Kindlin 3 Pleckstrin Homology Domain Has an Essential Role in Lymphocyte Function-associated Antigen 1 (LFA-1) Integrin-mediated B Cell Adhesion and Migration
Background: Kindlin 3 is mutated in LAD-III causing widespread infection, but its role in leukocyte function is incompletely… 
Review
2010
Review
2010
Chemokine arrest signals to leukocyte integrins trigger bi-directional-occupancy of individual heterodimers by extracellular and cytoplasmic ligands
Integrin heterodimers acquire high affinity to endothelial ligands by extensive conformational changes in both their α and… 
2009
2009
The Caenorhabditis elegans Ste20-Related Kinase and Rac-Type Small GTPase Regulate the c-Jun N-Terminal Kinase Signaling Pathway Mediating the Stress Response
ABSTRACT Mitogen-activated protein kinases (MAPKs) are integral to the mechanisms by which cells respond to physiological stimuli… 
2009
2009
LAD syndromes: FERMT3 kindles the signal.
LAD syndromes are uncommon but important genetic disorders of host defense. In this issue of Blood , Kuijpers and colleagues now… 
Highly Cited
2003
Highly Cited
2003
Proteomic analysis of the cell-surface membrane in chronic lymphocytic leukemia: identification of two novel proteins, BCNP1 and MIG2B
B-cell-specific plasma-membrane proteins are potential targets for either small molecule or antibody-based therapies. We have… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)