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FDFT1 gene

Known as: SQUALENE SYNTHASE, FDFT1, farnesyl-diphosphate farnesyltransferase 1 
 
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
Ginseng (Panax ginseng C.A. Meyer) is one of the most popular medicinal herbs and contains pharmacologically active components… Expand
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Highly Cited
2009
Highly Cited
2009
Artemisinin is an effective anti-malarial drug isolated from Artemisia annua L. (Chinese wormwood), but the content of… Expand
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Highly Cited
2008
Highly Cited
2008
Staphylococcus aureus produces hospital- and community-acquired infections, with methicillin-resistant S. aureus posing a serious… Expand
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Highly Cited
2008
Highly Cited
2008
Cholesterol metabolism is deregulated in carcinogenesis, and cancer cells exhibit enhanced mitochondrial cholesterol content… Expand
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Highly Cited
2008
Highly Cited
2008
Saccharomyces cerevisiae utilizes several regulatory mechanisms to maintain tight control over the intracellular level of… Expand
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Highly Cited
2004
Highly Cited
2004
Roots of Panax ginseng, one of the most famous medicinal plants, contain various phytosterols and bioactive triterpene saponins… Expand
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Highly Cited
2004
Highly Cited
2004
ContextPolymorphisms in genes involved in cholesterol synthesis, absorption, and transport may affect statin efficacy.ObjectiveTo… Expand
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Highly Cited
2002
Highly Cited
2002
The saponins of the model legume Medicago truncatula are glycosides of at least five different triterpene aglycones… Expand
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Highly Cited
1998
Highly Cited
1998
ABSTRACT The yeast Candida utilis does not possess an endogenous biochemical pathway for the synthesis of carotenoids. The… Expand
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Highly Cited
1992
Highly Cited
1992
Some bisphosphonates used for the treatment of bone disorders are also potent inhibitors of squalene synthase, a critical enzyme… Expand
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