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FDFT1 gene

Known as: SQUALENE SYNTHASE, FDFT1, farnesyl-diphosphate farnesyltransferase 1 
National Institutes of Health

Papers overview

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2003
2003
We recently demonstrated that squalene synthase (SQS) inhibitors reduce plasma triglyceride through an LDL receptor-independent… 
Highly Cited
2002
Highly Cited
2002
Squalene synthase (SQase) catalyzes two consecutive reactions in sterol biosynthesis. The first is the condensation of two… 
Highly Cited
2000
Highly Cited
2000
Squalene synthase (SQS; EC 2.5.1.21) plays an important role in the cholesterol biosynthetic pathway. We discovered ER-28448, 5… 
2000
2000
ABSTRACT Pneumocystis carinii synthesizes sterols with a double bond at C-7 of the sterol nucleus and an alkyl group with one or… 
1998
1998
Squalene synthase catalyzes the first committed step in cholesterol biosynthesis and thus is important as a potential target for… 
Highly Cited
1994
Highly Cited
1994
Squalene synthase catalyzes the committed step in the biosynthesis of sterols. Treating rats with zaragozic acid A, a potent…